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001     181669
005     20240229145653.0
024 7 _ |a 10.1016/j.ejca.2022.08.015
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024 7 _ |a 0014-2964
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024 7 _ |a 0959-8049
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024 7 _ |a 1879-0852
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024 7 _ |a (1990)
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024 7 _ |a 1879-2995
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024 7 _ |a (1965)
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037 _ _ |a DKFZ-2022-02153
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Hemminki, Janne
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245 _ _ |a Survival trends in solid cancers in the Nordic countries through 50 years.
260 _ _ |a Amsterdam [u.a.]
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520 _ _ |a Global survival studies in cancer have generally shown favourable development, but studies over extended periods on populations for which medical care is essentially free of charge are lacking.We analyse relative 1- and 5-year survival in all solid cancers in Denmark, Finland, Norway and Sweden through a 50-year period (1970-2019) using the NORDCAN database.The most recent survival results showed three types of patterns. Cancers of very good survival (5-year survival ∼90%) included common cancers of the breast and prostate, as well as melanoma. The second pattern, which included the largest number of cancers, showed 1-year survival of over 80% and a drop of 10-20 % units in 5-year survival. The third group consisted of eight fatal cancers, sharing poor 5-year survival (around 20%). The 50-year improvement in 1-year survival was largest (30-50 % units) in kidney, brain, gallbladder and liver cancers, and (∼30%) in colon, small intestinal, lung, pleural, pancreas and ovarian cancers. Improvements in 5-year survival were highest (40-50 % units) in prostate and kidney cancers but remained at 10-20 % units for the eight fatal cancers. Survival showed significant sex preferences for a few cancers.The analysis over a half-century confirms the progress in 'real-world' cancer control, and in 84% of patients 5-year survival was >60%. Metastases remain a challenge, placing the emphasis on early detection before metastasis occurs. Novel therapies, such as immunotherapy which has curative potential even against metastatic disease, are needed.
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650 _ 7 |a Cancer control
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650 _ 7 |a Periodic survival
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650 _ 7 |a Prognosis
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650 _ 7 |a Treatment
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700 1 _ |a Försti, Asta
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700 1 _ |a Hemminki, Akseli
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700 1 _ |a Hemminki, Kari
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773 _ _ |a 10.1016/j.ejca.2022.08.015
|g Vol. 175, p. 77 - 85
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|t European journal of cancer
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