%0 Journal Article
%A Tietze, A.
%A Mankad, K.
%A Lequin, M. H.
%A Ivarsson, L.
%A Mirsky, D.
%A Jaju, A.
%A Kool, Marcel
%A Hoff, K. V.
%A Bison, B.
%A Löbel, U.
%T Imaging Characteristics of CNS Neuroblastoma- FOXR2 : A Retrospective and Multi-Institutional Description of 25 Cases
%J American journal of neuroradiology
%V 23
%N 10
%@ 0195-6108
%C Oak Brook, Ill.
%I Soc.
%M DKFZ-2022-02223
%P 1476-1480
%D 2022
%Z 2022 Sep 22;43(10):1476-1480
%X Background and purpose: The 5th edition of the World Health Organization Classification of CNS tumors defines the CNS neuroblastoma FOXR2 in the group of embryonal tumors. Published clinical outcomes tend to suggest a favorable outcome after resection, craniospinal irradiation, and chemotherapy. This multicenter study aimed to describe imaging features of CNS neuroblastoma-FOXR2, which have been poorly characterized thus far.Materials and methods: On the basis of a previously published cohort of tumors molecularly classified as CNS neuroblastoma-FOXR2, patients with available imaging data were identified. The imaging features on preoperative MR imaging and CT data were recorded by 8 experienced pediatric neuroradiologists in consensus review meetings.Results: Twenty-five patients were evaluated (13 girls; median age, 4.5 years). The tumors were often large (mean, 115 [ SD, 83] mL), showed no (24
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:36137662
%R 10.3174/ajnr.A7644
%U https://inrepo02.dkfz.de/record/181803