TY - JOUR
AU - Tietze, A.
AU - Mankad, K.
AU - Lequin, M. H.
AU - Ivarsson, L.
AU - Mirsky, D.
AU - Jaju, A.
AU - Kool, Marcel
AU - Hoff, K. V.
AU - Bison, B.
AU - Löbel, U.
TI - Imaging Characteristics of CNS Neuroblastoma- FOXR2 : A Retrospective and Multi-Institutional Description of 25 Cases
JO - American journal of neuroradiology
VL - 23
IS - 10
SN - 0195-6108
CY - Oak Brook, Ill.
PB - Soc.
M1 - DKFZ-2022-02223
SP - 1476-1480
PY - 2022
N1 - 2022 Sep 22;43(10):1476-1480
AB - Background and purpose: The 5th edition of the World Health Organization Classification of CNS tumors defines the CNS neuroblastoma FOXR2 in the group of embryonal tumors. Published clinical outcomes tend to suggest a favorable outcome after resection, craniospinal irradiation, and chemotherapy. This multicenter study aimed to describe imaging features of CNS neuroblastoma-FOXR2, which have been poorly characterized thus far.Materials and methods: On the basis of a previously published cohort of tumors molecularly classified as CNS neuroblastoma-FOXR2, patients with available imaging data were identified. The imaging features on preoperative MR imaging and CT data were recorded by 8 experienced pediatric neuroradiologists in consensus review meetings.Results: Twenty-five patients were evaluated (13 girls; median age, 4.5 years). The tumors were often large (mean, 115 [ SD, 83] mL), showed no (24
LB - PUB:(DE-HGF)16
C6 - pmid:36137662
DO - DOI:10.3174/ajnr.A7644
UR - https://inrepo02.dkfz.de/record/181803
ER -