%0 Journal Article
%A Mattke, Matthias
%A Ohlinger, Matteo
%A Bougatf, Nina
%A Harrabi, Semi
%A Wolf, Robert
%A Seidensaal, Katharina
%A Welzel, Thomas
%A Röder, Falk
%A Gerum, Sabine
%A Ellerbrock, Malte
%A Jäkel, Oliver
%A Haberer, Thomas
%A Herfarth, Klaus
%A Uhl, Matthias
%A Debus, Jürgen
%T Proton and carbon ion beam treatment with active raster scanning method in 147 patients with skull base chordoma at the Heidelberg Ion Beam Therapy Center-a single-center experience.
%J Strahlentherapie und Onkologie
%V 199
%N 2
%@ 0179-7158
%C Heidelberg
%I Springer Medizin
%M DKFZ-2022-02237
%P 160-168
%D 2023
%Z #LA:E050# /2023 Feb;199(2):160-168
%X This study aimed to compare the results of irradiation with protons versus irradiation with carbon ions in a raster scan technique in patients with skull base chordomas and to identify risk factors that may compromise treatment results.A total of 147 patients (85 men, 62 women) were irradiated with carbon ions (111 patients) or protons (36 patients) with a median dose of 66 Gy (RBE (Relative biological effectiveness); carbon ions) in 4 weeks or 74 Gy (RBE; protons) in 7 weeks at the Heidelberg Ion Beam Therapy Center (HIT) in Heidelberg, Germany. The median follow-up time was 49.3 months. All patients had gross residual disease at the beginning of RT. Compression of the brainstem was present in 38
%K Bragg peak (Other)
%K C12 (Other)
%K Heavy ion (Other)
%K High LET (Other)
%K Notochordal sarcoma (Other)
%K Particle therapy (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:36149438
%R 10.1007/s00066-022-02002-4
%U https://inrepo02.dkfz.de/record/181822