TY  - JOUR
AU  - Mattke, Matthias
AU  - Ohlinger, Matteo
AU  - Bougatf, Nina
AU  - Harrabi, Semi
AU  - Wolf, Robert
AU  - Seidensaal, Katharina
AU  - Welzel, Thomas
AU  - Röder, Falk
AU  - Gerum, Sabine
AU  - Ellerbrock, Malte
AU  - Jäkel, Oliver
AU  - Haberer, Thomas
AU  - Herfarth, Klaus
AU  - Uhl, Matthias
AU  - Debus, Jürgen
TI  - Proton and carbon ion beam treatment with active raster scanning method in 147 patients with skull base chordoma at the Heidelberg Ion Beam Therapy Center-a single-center experience.
JO  - Strahlentherapie und Onkologie
VL  - 199
IS  - 2
SN  - 0179-7158
CY  - Heidelberg
PB  - Springer Medizin
M1  - DKFZ-2022-02237
SP  - 160-168
PY  - 2023
N1  - #LA:E050# /2023 Feb;199(2):160-168
AB  - This study aimed to compare the results of irradiation with protons versus irradiation with carbon ions in a raster scan technique in patients with skull base chordomas and to identify risk factors that may compromise treatment results.A total of 147 patients (85 men, 62 women) were irradiated with carbon ions (111 patients) or protons (36 patients) with a median dose of 66 Gy (RBE (Relative biological effectiveness); carbon ions) in 4 weeks or 74 Gy (RBE; protons) in 7 weeks at the Heidelberg Ion Beam Therapy Center (HIT) in Heidelberg, Germany. The median follow-up time was 49.3 months. All patients had gross residual disease at the beginning of RT. Compression of the brainstem was present in 38
KW  - Bragg peak (Other)
KW  - C12 (Other)
KW  - Heavy ion (Other)
KW  - High LET (Other)
KW  - Notochordal sarcoma (Other)
KW  - Particle therapy (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:36149438
DO  - DOI:10.1007/s00066-022-02002-4
UR  - https://inrepo02.dkfz.de/record/181822
ER  -