%0 Journal Article
%A Heisser, Thomas
%A Cardoso, Rafael
%A Niedermaier, Tobias
%A Hoffmeister, Michael
%A Brenner, Hermann
%T Making colonoscopy-based screening more efficient: a 'gateopener' approach.
%J International journal of cancer
%V 152
%N 5
%@ 0020-7136
%C Bognor Regis
%I Wiley-Liss
%M DKFZ-2022-02371
%P 952-961
%D 2023
%Z #EA:C070#LA:C070#LA:C120# / 2023 Mar 1;152(5):952-961
%X Screening colonoscopy for early detection and prevention of colorectal cancer (CRC) is mostly used inefficiently. Here, we assessed the potential of an innovative approach to colonoscopy-based screening, by use of a single, low threshold fecal immunochemical test (FIT) as a 'gateopener' for screening colonoscopy. Using COSIMO, a validated simulation model, we modelled scenarios including either direct invitation to screening colonoscopy or an alternative approach involving mailing a single ('gateopener') FIT along with an invitation to colonoscopy contingent on a FIT value above a low threshold yielding a 50
%K colonoscopy (Other)
%K colorectal cancer (Other)
%K fecal immunochemical testing (Other)
%K modelling (Other)
%K screening (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:36214791
%R 10.1002/ijc.34317
%U https://inrepo02.dkfz.de/record/182029