TY  - JOUR
AU  - Heisser, Thomas
AU  - Cardoso, Rafael
AU  - Niedermaier, Tobias
AU  - Hoffmeister, Michael
AU  - Brenner, Hermann
TI  - Making colonoscopy-based screening more efficient: a 'gateopener' approach.
JO  - International journal of cancer
VL  - 152
IS  - 5
SN  - 0020-7136
CY  - Bognor Regis
PB  - Wiley-Liss
M1  - DKFZ-2022-02371
SP  - 952-961
PY  - 2023
N1  - #EA:C070#LA:C070#LA:C120# / 2023 Mar 1;152(5):952-961
AB  - Screening colonoscopy for early detection and prevention of colorectal cancer (CRC) is mostly used inefficiently. Here, we assessed the potential of an innovative approach to colonoscopy-based screening, by use of a single, low threshold fecal immunochemical test (FIT) as a 'gateopener' for screening colonoscopy. Using COSIMO, a validated simulation model, we modelled scenarios including either direct invitation to screening colonoscopy or an alternative approach involving mailing a single ('gateopener') FIT along with an invitation to colonoscopy contingent on a FIT value above a low threshold yielding a 50
KW  - colonoscopy (Other)
KW  - colorectal cancer (Other)
KW  - fecal immunochemical testing (Other)
KW  - modelling (Other)
KW  - screening (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:36214791
DO  - DOI:10.1002/ijc.34317
UR  - https://inrepo02.dkfz.de/record/182029
ER  -