% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Hoffmann:182485,
      author       = {I. Hoffmann$^*$},
      title        = {{R}ole of {P}olo-like {K}inases {P}lk1 and {P}lk4 in the
                      {I}nitiation of {C}entriole {D}uplication-{I}mpact on
                      {C}ancer},
      journal      = {Cells},
      volume       = {11},
      number       = {5},
      issn         = {2073-4409},
      address      = {Basel},
      publisher    = {MDPI},
      reportid     = {DKFZ-2022-02680},
      pages        = {786},
      year         = {2022},
      note         = {#LA:F045#},
      abstract     = {Centrosomes nucleate and anchor microtubules and therefore
                      play major roles in spindle formation and chromosome
                      segregation during mitosis. Duplication of the centrosome
                      occurs, similar to DNA, only once during the cell cycle.
                      Aberration of the centrosome number is common in human
                      tumors. At the core of centriole duplication is the
                      conserved polo-like kinase 4, Plk4, and two structural
                      proteins, STIL and Sas-6. In this review, I summarize and
                      discuss developments in our understanding of the first steps
                      of centriole duplication and their regulation},
      subtyp        = {Review Article},
      cin          = {F045},
      ddc          = {570},
      cid          = {I:(DE-He78)F045-20160331},
      pnm          = {316 - Infektionen, Entzündung und Krebs (POF4-316)},
      pid          = {G:(DE-HGF)POF4-316},
      typ          = {PUB:(DE-HGF)16},
      doi          = {https://doi.org/10.3390/cells11050786},
      url          = {https://inrepo02.dkfz.de/record/182485},
}