%0 Journal Article
%A Diabetes, GBD 2019
%T Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019.
%J The lancet / Planetary health
%V 6
%N 7
%@ 2542-5196
%C Amsterdam
%I Elsevier
%M DKFZ-2022-02796
%P e586 - e600
%D 2022
%Z The Lancet. Planetary health / ISSN:2542-5196 (Electronic) / 2542-5196 (Linking)
%X Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2·5 originating from ambient and household air pollution.We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM2·5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure-response curve from the extracted relative risk estimates using the MR-BRT (meta-regression-Bayesian, regularised, trimmed) tool. The estimated curve was linked to ambient and household PM2·5 exposures from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, and estimates of the attributable burden (population attributable fractions and rates per 100 000 population of deaths and disability-adjusted life-years) for 204 countries from 1990 to 2019 were calculated. We also assessed the role of changes in exposure, population size, age, and type 2 diabetes incidence in the observed trend in PM2·5-attributable type 2 diabetes burden. All estimates are presented with 95
%K Air Pollution: adverse effects
%K Bayes Theorem
%K Diabetes Mellitus, Type 2: chemically induced
%K Diabetes Mellitus, Type 2: epidemiology
%K Global Burden of Disease
%K Humans
%K Particulate Matter: adverse effects
%K Quality-Adjusted Life Years
%K Particulate Matter (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:35809588
%2 pmc:PMC9278144
%R 10.1016/S2542-5196(22)00122-X
%U https://inrepo02.dkfz.de/record/182619