TY  - JOUR
AU  - Diabetes, GBD 2019
TI  - Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019.
JO  - The lancet / Planetary health
VL  - 6
IS  - 7
SN  - 2542-5196
CY  - Amsterdam
PB  - Elsevier
M1  - DKFZ-2022-02796
SP  - e586 - e600
PY  - 2022
N1  - The Lancet. Planetary health / ISSN:2542-5196 (Electronic) / 2542-5196 (Linking)
AB  - Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2·5 originating from ambient and household air pollution.We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM2·5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure-response curve from the extracted relative risk estimates using the MR-BRT (meta-regression-Bayesian, regularised, trimmed) tool. The estimated curve was linked to ambient and household PM2·5 exposures from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, and estimates of the attributable burden (population attributable fractions and rates per 100 000 population of deaths and disability-adjusted life-years) for 204 countries from 1990 to 2019 were calculated. We also assessed the role of changes in exposure, population size, age, and type 2 diabetes incidence in the observed trend in PM2·5-attributable type 2 diabetes burden. All estimates are presented with 95
KW  - Air Pollution: adverse effects
KW  - Bayes Theorem
KW  - Diabetes Mellitus, Type 2: chemically induced
KW  - Diabetes Mellitus, Type 2: epidemiology
KW  - Global Burden of Disease
KW  - Humans
KW  - Particulate Matter: adverse effects
KW  - Quality-Adjusted Life Years
KW  - Particulate Matter (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:35809588
C2  - pmc:PMC9278144
DO  - DOI:10.1016/S2542-5196(22)00122-X
UR  - https://inrepo02.dkfz.de/record/182619
ER  -