Home > Publications database > Change Toward Healthier Lifestyles Is Associated With Better Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors. > print |
001 | 182621 | ||
005 | 20240229145725.0 | ||
024 | 7 | _ | |a 10.6004/jnccn.2022.7049 |2 doi |
024 | 7 | _ | |a pmid:36351340 |2 pmid |
024 | 7 | _ | |a 1540-1405 |2 ISSN |
024 | 7 | _ | |a 1540-1413 |2 ISSN |
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037 | _ | _ | |a DKFZ-2022-02798 |
041 | _ | _ | |a English |
082 | _ | _ | |a 610 |
100 | 1 | _ | |a Eyl-Armbruster, Ruth Elisa |0 P:(DE-HGF)0 |b 0 |e First author |
245 | _ | _ | |a Change Toward Healthier Lifestyles Is Associated With Better Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors. |
260 | _ | _ | |a Cold Spring Harbor, NY |c 2022 |b Harborside Press |
336 | 7 | _ | |a article |2 DRIVER |
336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1668589467_7316 |2 PUB:(DE-HGF) |
336 | 7 | _ | |a ARTICLE |2 BibTeX |
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500 | _ | _ | |a #EA:C070#EA:C071#LA:C071# |
520 | _ | _ | |a Little is known about how changes in a constellation of lifestyle factors affect health-related quality of life (HRQoL) in colorectal cancer (CRC) survivors. Our study aimed to investigate the association between changes in healthy lifestyle and HRQoL over time in survivors of stage I-IV CRC.We included 2,283 long-term (≥5 years postdiagnosis) survivors. A healthy lifestyle score (HLS) comprising smoking, alcohol consumption, diet, physical activity, and body fatness was derived at diagnosis and 5-year follow-up (5YFU) and categorized as low, moderate, or high. We assessed HRQoL with the EORTC Quality of Life Questionnaire-Core 30 at 5YFU and 10-year follow-up. We used multivariable linear regression and linear mixed models to explore associations between changes in HLS and HRQoL over follow-up.A low baseline HLS was associated with poorer functioning and global health/QoL and a higher symptom burden at 5YFU compared with a high baseline HLS. An improved HLS from baseline to 5YFU was associated with better functioning, higher global health/QoL, and fewer symptoms at 5YFU than a maintained-high HLS. In longitudinal analyses, improved HLS was associated with better functioning at follow-up. Survivors with a maintained-high or an improved HLS reported generally less fatigue, pain, and dyspnea at follow-ups compared with survivors with a maintained-low or decreased HLS.Change toward a healthier lifestyle since diagnosis was associated with better HRQoL in long-term CRC survivors. Our results support the importance of maintaining and/or promoting a healthier lifestyle among CRC survivors postdiagnosis. |
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650 | _ | 7 | |a Colorectal Cancer |2 Other |
650 | _ | 7 | |a healthy lifestyle |2 Other |
650 | _ | 7 | |a long-term survivors |2 Other |
650 | _ | 7 | |a longitudinal |2 Other |
650 | _ | 7 | |a quality of life |2 Other |
650 | _ | 2 | |a Humans |2 MeSH |
650 | _ | 2 | |a Quality of Life |2 MeSH |
650 | _ | 2 | |a Healthy Lifestyle |2 MeSH |
650 | _ | 2 | |a Life Style |2 MeSH |
650 | _ | 2 | |a Survivors |2 MeSH |
650 | _ | 2 | |a Colorectal Neoplasms: complications |2 MeSH |
650 | _ | 2 | |a Surveys and Questionnaires |2 MeSH |
700 | 1 | _ | |a Thong, Melissa |0 P:(DE-He78)24fe6057396bec79d2638615b12eb989 |b 1 |e First author |u dkfz |
700 | 1 | _ | |a Carr, Prudence |0 P:(DE-He78)7d7ee36ed0313bbc4c91bc3df5950107 |b 2 |
700 | 1 | _ | |a Jansen, Lina |0 P:(DE-He78)bbfe0ebad1e3b608bca2b49d4f86bd09 |b 3 |u dkfz |
700 | 1 | _ | |a Chang-Claude, Jenny |0 P:(DE-He78)c259d6cc99edf5c7bc7ce22c7f87c253 |b 4 |u dkfz |
700 | 1 | _ | |a Hoffmeister, Michael |0 P:(DE-He78)6c5d058b7552d071a7fa4c5e943fff0f |b 5 |u dkfz |
700 | 1 | _ | |a Brenner, Hermann |0 P:(DE-He78)90d5535ff896e70eed81f4a4f6f22ae2 |b 6 |u dkfz |
700 | 1 | _ | |a Arndt, Volker |0 P:(DE-He78)d023fdf423d87ee6c710e34dd7581fa0 |b 7 |e Last author |u dkfz |
773 | _ | _ | |a 10.6004/jnccn.2022.7049 |g Vol. 20, no. 11, p. 1233 - 1243.e10 |0 PERI:(DE-600)2134524-7 |n 11 |p 1233 - 1243.e10 |t Journal of the National Comprehensive Cancer Network |v 20 |y 2022 |x 1540-1405 |
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