%0 Journal Article
%A Hoegen, Philipp
%A Katsigiannopulos, Efthimios
%A Buchele, Carolin
%A Regnery, Sebastian
%A Weykamp, Fabian
%A Sandrini, Elisabetta
%A Ristau, Jonas
%A Liermann, Jakob
%A Meixner, Eva
%A Forster, Tobias
%A Renkamp, C. Katharina
%A Schlüter, Fabian
%A Rippke, Carolin
%A Debus, Jürgen
%A Klüter, Sebastian
%A Hörner-Rieber, Juliane
%T Stereotactic magnetic resonance-guided online adaptive radiotherapy of adrenal metastases combines high ablative doses with optimized sparing of organs at risk
%J Clinical and translational radiation oncology
%V 39
%@ 2405-6308
%C Amsterdam
%I Elsevier
%M DKFZ-2023-00009
%P 100567
%D 2023
%Z #EA:E050#LA:E050#
%X Purpose/Objective: To evaluate the potential of stereotactic magnetic resonance-guided online adaptive radiotherapy (SMART) to fulfill dose recommendations for stereotactic body radiotherapy (SBRT) of adrenal metastases and spare organs at risk (OAR). Materials and methods: In this subgroup analysis of a prospective registry trial, 22 patients with adrenal metastases were treated on a 0.35 T MR-Linac in 5–12 fractions with fraction doses of 4–10 Gy. Baseline plans were re-calculated to the anatomy of the day. These predicted plans were reoptimized to generate adapted plans. Baseline, predicted and adapted plans were compared with regard to PTV objectives, OAR constraints and published dose recommendations. Results: The cohort comprised patients with large GTV (median 36.0 cc) and PTV (median 66.6 cc) and predominantly left-sided metastases. 179 of 181 fractions (98.9 
%F PUB:(DE-HGF)16
%9 Journal Article
%R 10.1016/j.ctro.2022.100567
%U https://inrepo02.dkfz.de/record/186557