TY  - JOUR
AU  - Hoegen, Philipp
AU  - Katsigiannopulos, Efthimios
AU  - Buchele, Carolin
AU  - Regnery, Sebastian
AU  - Weykamp, Fabian
AU  - Sandrini, Elisabetta
AU  - Ristau, Jonas
AU  - Liermann, Jakob
AU  - Meixner, Eva
AU  - Forster, Tobias
AU  - Renkamp, C. Katharina
AU  - Schlüter, Fabian
AU  - Rippke, Carolin
AU  - Debus, Jürgen
AU  - Klüter, Sebastian
AU  - Hörner-Rieber, Juliane
TI  - Stereotactic magnetic resonance-guided online adaptive radiotherapy of adrenal metastases combines high ablative doses with optimized sparing of organs at risk
JO  - Clinical and translational radiation oncology
VL  - 39
SN  - 2405-6308
CY  - Amsterdam
PB  - Elsevier
M1  - DKFZ-2023-00009
SP  - 100567
PY  - 2023
N1  - #EA:E050#LA:E050#
AB  - Purpose/Objective: To evaluate the potential of stereotactic magnetic resonance-guided online adaptive radiotherapy (SMART) to fulfill dose recommendations for stereotactic body radiotherapy (SBRT) of adrenal metastases and spare organs at risk (OAR). Materials and methods: In this subgroup analysis of a prospective registry trial, 22 patients with adrenal metastases were treated on a 0.35 T MR-Linac in 5–12 fractions with fraction doses of 4–10 Gy. Baseline plans were re-calculated to the anatomy of the day. These predicted plans were reoptimized to generate adapted plans. Baseline, predicted and adapted plans were compared with regard to PTV objectives, OAR constraints and published dose recommendations. Results: The cohort comprised patients with large GTV (median 36.0 cc) and PTV (median 66.6 cc) and predominantly left-sided metastases. 179 of 181 fractions (98.9 
LB  - PUB:(DE-HGF)16
DO  - DOI:10.1016/j.ctro.2022.100567
UR  - https://inrepo02.dkfz.de/record/186557
ER  -