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@ARTICLE{Castaeda:212454,
      author       = {J. Castañeda and M. Gil-Lespinard and E. Almanza-Aguilera
                      and F. Llaha and J.-H. Gómez and N. Bondonno and A.
                      Tjønneland and K. Overvad and V. Katzke$^*$ and M. B.
                      Schulze and G. Masala and C. Agnoli and M. Santucci de
                      Magistris and R. Tumino and C. Sacerdote and G. Skeie and M.
                      Brustad and C. Lasheras and E. Molina-Montes and M.-D.
                      Chirlaque and A. Barricarte and E. Sonestedt and M. da Silva
                      and I. Johansson and J. Hultdin and A. M. May and N. G.
                      Forouhi and A. K. Heath and H. Freisling and E. Weiderpass
                      and A. Scalbert and R. Zamora-Ros},
      title        = {{A}ssociation between classes and subclasses of polyphenol
                      intake and 5-year body weight changes in the
                      {EPIC}-{PANACEA} study.},
      journal      = {Obesity},
      volume       = {31},
      number       = {4},
      issn         = {1071-7323},
      address      = {Hoboken, NJ},
      publisher    = {Wiley},
      reportid     = {DKFZ-2023-00171},
      pages        = {1146-1158},
      year         = {2023},
      note         = {2023 Apr;31(4):1146-1158},
      abstract     = {The aim of this study was to evaluate the associations
                      among the intake of total polyphenols, polyphenol classes,
                      and polyphenol subclasses and body weight change over 5
                      years.A total of 349,165 men and women aged 25 to 70 years
                      were recruited in the Physical Activity, Nutrition, Alcohol,
                      Cessation of Smoking, Eating Out of Home and Obesity
                      (PANACEA) project of the European Prospective Investigation
                      into Cancer and Nutrition (EPIC) cohort from nine European
                      countries. Body weight was measured at baseline and at
                      follow-up after a median time of 5 years. Polyphenol intake,
                      including four main polyphenol classes and eighteen
                      subclasses, was estimated using validated dietary
                      questionnaires and Phenol-Explorer. Multilevel mixed linear
                      regression models were used to estimate the
                      associations.Participants gained, on average, 2.6 kg (±5.0
                      kg) over 5 years. Total flavonoids intake was inversely
                      associated with body weight change (-0.195 kg/5 years,
                      $95\%$ CI: -0.262 to -0.128). However, the intake of total
                      polyphenols (0.205 kg/5 years, $95\%$ CI: 0.138 to 0.272)
                      and intake of hydroxycinnamic acids (0.324 kg/5 years,
                      $95\%$ CI: 0.267 to 0.381) were positively associated with
                      body weight gain. In analyses stratified by coffee
                      consumption, hydroxycinnamic acid intake was positively
                      associated with body weight gain in coffee consumers (0.379
                      kg/5 years, $95\%$ CI: 0.319 to 0.440), but not in coffee
                      nonconsumers (-0.179 kg/5 years, $95\%$ CI: -0.490 to
                      0.133).Higher intakes of flavonoids and their subclasses are
                      inversely associated with a modest body weight change.
                      Results regarding hydroxycinnamic acids in coffee consumers
                      require further investigation.},
      cin          = {C020},
      ddc          = {610},
      cid          = {I:(DE-He78)C020-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:36693804},
      doi          = {10.1002/oby.23689},
      url          = {https://inrepo02.dkfz.de/record/212454},
}