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@ARTICLE{SparberSauer:265697,
      author       = {M. Sparber-Sauer and A. Ferrari and S. L. Spunt and C.
                      Vokuhl and D. Casey and T. B. Lautz and W. H. Meyer and D.
                      O. Walterhouse and K. W. Pajtler$^*$ and R. Alaggio and A.
                      Schmidt and A. Safwat and B. Timmermann$^*$ and P. Dall'Igna
                      and S. Chen and A. R. Weiss and D. Orbach},
      title        = {{T}he significance of margins in pediatric
                      {N}on-{R}habdomyosarcoma soft tissue sarcomas: {C}onsensus
                      on surgical margin definition harmonization from the
                      {IN}ternational {S}oft {T}issue {S}a{R}coma {C}onsor{T}ium
                      ({INSTR}u{CT}).},
      journal      = {Cancer medicine},
      volume       = {12},
      number       = {10},
      issn         = {2045-7634},
      address      = {Hoboken, NJ},
      publisher    = {Wiley},
      reportid     = {DKFZ-2023-00292},
      pages        = {11719-11730},
      year         = {2023},
      note         = {2023 May;12(10):11719-11730},
      abstract     = {Margin status following surgery in children, adolescents,
                      and young adults with soft tissue sarcomas is controversial
                      and has been defined differently by various specialties,
                      with definitions changing over time and by cooperative
                      group. The International Soft Tissue Sarcoma Consortium
                      (INSTRuCT) is a collaboration of the Children's Oncology
                      Group (COG) Soft Tissue Sarcoma Committee, European
                      pediatric Soft Tissue sarcoma Study Group (EpSSG), and the
                      European Cooperative Weichteilsarkom Studiengruppe (CWS)
                      devoted to improving patient outcomes by pooling and mining
                      cooperative group clinical trial data.The INSTRuCT
                      non-rhabdomyosarcoma soft tissue sarcoma (NRSTS) working
                      group aimed to develop international harmonized
                      recommendations regarding surgical margin assessment and
                      definitions in children and adolescents with soft tissue
                      tumors.This review addresses accepted principles and areas
                      of controversy, including the perspectives of surgeons,
                      pathologists, radiation oncologists, and pediatric
                      oncologists, to develop a framework for building common
                      guidelines for future research.},
      subtyp        = {Review Article},
      keywords     = {margins (Other) / pediatric/adolescent oncology (Other) /
                      radiotherapy (Other) / soft tissue sarcoma (Other) / surgery
                      (Other)},
      cin          = {B062 / HD01 / ED01},
      ddc          = {610},
      cid          = {I:(DE-He78)B062-20160331 / I:(DE-He78)HD01-20160331 /
                      I:(DE-He78)ED01-20160331},
      pnm          = {312 - Funktionelle und strukturelle Genomforschung
                      (POF4-312)},
      pid          = {G:(DE-HGF)POF4-312},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:36744538},
      doi          = {10.1002/cam4.5671},
      url          = {https://inrepo02.dkfz.de/record/265697},
}