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@ARTICLE{Hemminki:272839,
author = {K. Hemminki$^*$ and F. Tichanek and A. Försti$^*$ and O.
Hemminki and A. Hemminki},
title = {{S}urvival in gastric and esophageal cancers in the
{N}ordic countries through a half century.},
journal = {Cancer medicine},
volume = {12},
number = {9},
issn = {2045-7634},
address = {Hoboken, NJ},
publisher = {Wiley},
reportid = {DKFZ-2023-00412},
pages = {10212-10221},
year = {2023},
note = {#EA:C020# / 2023 May;12(9):10212-10221},
abstract = {Gastric cancer (GC) and esophageal cancer (EC) are among
the most fatal cancers and improving survival in them is a
major clinical challenge. Nordic cancer data were recently
released up to year 2019. These data are relevant for
long-term survival analysis as they originate from
high-quality national cancer registries from countries with
practically free access to health care, thus documenting
'real-world' experience for entire populations.Data were
obtained for Danish (DK), Finnish (FI), Norwegian (NO), and
Swedish (SE) patients from the NORDCAN database from years
1970 through 2019. Relative 1- and 5-year survival were
analyzed, and additionally the difference between 1- and
5-year survival was calculated as a measure of trends
between years 1 and 5 after diagnosis.Relative 1-year
survival for Nordic men and women in GC was $30\%$ in period
1970-74 and it increased close to $60\%.$ Early 5-year
survival ranged between 10 and $15\%$ and the last figures
were over $30\%$ for all women and NO men while survival for
other men remain below $30\%.$ Survival in EC was below that
in GC, and it reached over $50\%$ for 1-year survival only
for NO patients; 5-year survival reached over $20\%$ only
for NO women. For both cancers, the difference between 1-
and 5-year survival increased with time. Survival was worst
among old patients.GC and EC survival improved over the
50-year period but the increase in 5-year survival was
entirely explained by gains in 1-year survival, which
improved at an accelerated pace in EC. The likely reasons
for improvements are changes in diagnosis, treatment, and
care. The challenges are to push survival past year 1 with
attention to old patients. These cancers have a potential
for primary prevention through the avoidance of risk
factors.},
keywords = {mortality (Other) / relative survival (Other) / risk
factors (Other) / stomach cancer (Other) / treatment
(Other)},
cin = {C020 / B062 / HD01},
ddc = {610},
cid = {I:(DE-He78)C020-20160331 / I:(DE-He78)B062-20160331 /
I:(DE-He78)HD01-20160331},
pnm = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
pid = {G:(DE-HGF)POF4-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:36846972},
doi = {10.1002/cam4.5748},
url = {https://inrepo02.dkfz.de/record/272839},
}