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| 001 | 272839 | ||
| 005 | 20240229154925.0 | ||
| 024 | 7 | _ | |a 10.1002/cam4.5748 |2 doi |
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| 037 | _ | _ | |a DKFZ-2023-00412 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Hemminki, Kari |0 P:(DE-He78)19b0ec1cea271419d9fa8680e6ed6865 |b 0 |e First author |u dkfz |
| 245 | _ | _ | |a Survival in gastric and esophageal cancers in the Nordic countries through a half century. |
| 260 | _ | _ | |a Hoboken, NJ |c 2023 |b Wiley |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1685453524_28113 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 500 | _ | _ | |a #EA:C020# / 2023 May;12(9):10212-10221 |
| 520 | _ | _ | |a Gastric cancer (GC) and esophageal cancer (EC) are among the most fatal cancers and improving survival in them is a major clinical challenge. Nordic cancer data were recently released up to year 2019. These data are relevant for long-term survival analysis as they originate from high-quality national cancer registries from countries with practically free access to health care, thus documenting 'real-world' experience for entire populations.Data were obtained for Danish (DK), Finnish (FI), Norwegian (NO), and Swedish (SE) patients from the NORDCAN database from years 1970 through 2019. Relative 1- and 5-year survival were analyzed, and additionally the difference between 1- and 5-year survival was calculated as a measure of trends between years 1 and 5 after diagnosis.Relative 1-year survival for Nordic men and women in GC was 30% in period 1970-74 and it increased close to 60%. Early 5-year survival ranged between 10 and 15% and the last figures were over 30% for all women and NO men while survival for other men remain below 30%. Survival in EC was below that in GC, and it reached over 50% for 1-year survival only for NO patients; 5-year survival reached over 20% only for NO women. For both cancers, the difference between 1- and 5-year survival increased with time. Survival was worst among old patients.GC and EC survival improved over the 50-year period but the increase in 5-year survival was entirely explained by gains in 1-year survival, which improved at an accelerated pace in EC. The likely reasons for improvements are changes in diagnosis, treatment, and care. The challenges are to push survival past year 1 with attention to old patients. These cancers have a potential for primary prevention through the avoidance of risk factors. |
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| 650 | _ | 7 | |a mortality |2 Other |
| 650 | _ | 7 | |a relative survival |2 Other |
| 650 | _ | 7 | |a risk factors |2 Other |
| 650 | _ | 7 | |a stomach cancer |2 Other |
| 650 | _ | 7 | |a treatment |2 Other |
| 700 | 1 | _ | |a Tichanek, Filip |b 1 |
| 700 | 1 | _ | |a Försti, Asta |0 P:(DE-He78)f26164c08f2f14abcf31e52e13ee3696 |b 2 |u dkfz |
| 700 | 1 | _ | |a Hemminki, Otto |b 3 |
| 700 | 1 | _ | |a Hemminki, Akseli |0 0000-0001-7103-8530 |b 4 |
| 773 | _ | _ | |a 10.1002/cam4.5748 |g p. cam4.5748 |0 PERI:(DE-600)2659751-2 |n 9 |p 10212-10221 |t Cancer medicine |v 12 |y 2023 |x 2045-7634 |
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