%0 Journal Article
%A Soltwedel, Johannes
%A Suckert, Theresa
%A Beyreuther, Elke
%A Schneider, Moritz
%A Boucsein, Marc Oliver
%A Bodenstein, Elisabeth
%A Nexhipi, Sindi
%A Stolz-Kieslich, Liane
%A Krause, Mechthild
%A Neubeck, Cläre von
%A Haase, Robert
%A Lühr, Armin
%A Dietrich, Antje
%T Slice2Volume: Fusion of Multimodal Medical Imaging and Light Microscopy Data of Irradiation-Injured Brain Tissue in 3D.
%J Radiotherapy and oncology
%V 182
%@ 0167-8140
%C Amsterdam [u.a.]
%I Elsevier Science
%M DKFZ-2023-00424
%P 109591
%D 2023
%Z 2023 Feb 28;182:109591
%X Comprehending cellular changes of radiation-induced brain injury is crucial to prevent and treat the pathology. We provide a unique open dataset of proton-irradiated mouse brains consisting of medical imaging, radiation dose simulations, and large-scale microscopy images, all registered into a common coordinate system. This allows dose-dependent analyses on single-cell level.
%K Multimodal Imaging (Other)
%K Normal tissue toxicity (Other)
%K Open Data (Other)
%K Preclinical mouse brain irradiation (Other)
%K proton therapy (Other)
%K radiation-induced brain injury (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:36858201
%R 10.1016/j.radonc.2023.109591
%U https://inrepo02.dkfz.de/record/274078