%0 Journal Article
%A Mascalchi, Mario
%A Romei, Chiara
%A Marzi, Chiara
%A Diciotti, Stefano
%A Picozzi, Giulia
%A Pistelli, Francesco
%A Zappa, Marco
%A Paci, Eugenio
%A Carozzi, Francesca
%A Gorini, Giuseppe
%A Falaschi, Fabio
%A Deliperi, Anna Lisa
%A Camiciottoli, Gianna
%A Carrozzi, Laura
%A Puliti, Donella
%T Pulmonary emphysema and coronary artery calcifications at baseline LDCT and long-term mortality in smokers and former smokers of the ITALUNG screening trial.
%J European radiology
%V 33
%N 5
%@ 0938-7994
%C Heidelberg
%I Springer
%M DKFZ-2023-00428
%P 3115-3123
%D 2023
%Z #EA:C020# / 2023 May;33(5):3115-3123
%X Cardiovascular disease (CVD), lung cancer (LC), and respiratory diseases are main causes of death in smokers and former smokers undergoing low-dose computed tomography (LDCT) for LC screening. We assessed whether quantification of pulmonary emphysematous changes at baseline LDCT has a predictive value concerning long-term mortality.In this longitudinal study, we assessed pulmonary emphysematous changes with densitometry (volume corrected relative area below - 950 Hounsfield units) and coronary artery calcifications (CAC) with a 0-3 visual scale in baseline LDCT of 524 participants in the ITALUNG trial and analyzed their association with mortality after 13.6 years of follow-up using conventional statistics and a machine learning approach.Pulmonary emphysematous changes were present in 32.3
%K Cardiovascular disease (Other)
%K Cause of death (Other)
%K Lung neoplasm (Other)
%K Pulmonary emphysema (Other)
%K Smokers (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:36854875
%R 10.1007/s00330-023-09504-4
%U https://inrepo02.dkfz.de/record/274082