TY  - JOUR
AU  - Solomonidou, Nantia
AU  - Germanou, Daphnie
AU  - Strouthos, Iosif
AU  - Karagiannis, Efstratios
AU  - Farolfi, Andrea
AU  - Koerber, Stefan A
AU  - Debus, Jürgen
AU  - Peeken, Jan C
AU  - Vogel, Marco E
AU  - Vrachimis, Alexis
AU  - Spohn, Simon K B
AU  - Shelan, Mohamed
AU  - Aebersold, Daniel
AU  - Grosu, Anca-Ligia
AU  - Ceci, Francesco
AU  - Kroeze, Stephanie G C
AU  - Guckenberger, Matthias
AU  - Fanti, Stefano
AU  - Belka, Claus
AU  - Hruby, George
AU  - Scharl, S.
AU  - Wiegel, Thomas
AU  - Bartenstein, Peter
AU  - Henkenberens, Christoph
AU  - Emmett, Louise
AU  - Schmidt-Hegemann, Nina Sophie
AU  - Ferentinos, Konstantinos
AU  - Zamboglou, Constantinos
TI  - PSMA-PET/CT-guided salvage radiotherapy in recurrent or persistent prostate cancer and PSA </td><td width="150">
TI  - lt; 0.2 ng/ml.
JO  - European journal of nuclear medicine and molecular imaging
VL  - 50
IS  - 8
SN  - 1619-7070
CY  - Heidelberg [u.a.]
PB  - Springer-Verl.
M1  - DKFZ-2023-00497
SP  - 2529-2536
PY  - 2023
N1  - 2023 Jul;50(8):2529-2536
AB  - The purpose of this retrospective, multicenter study was to assess efficacy of PSMA-PET/CT-guided salvage radiotherapy (sRT) in patients with recurrent or persistent PSA after primary surgery and PSA levels < 0.2 ng/ml.The study included patients from a pooled cohort (n = 1223) of 11 centers from 6 countries. Patients with PSA levels > 0.2 ng/ml prior to sRT or without sRT to the prostatic fossa were excluded. The primary study endpoint was biochemical recurrence-free survival (BRFS) and BR was defined as PSA nadir after sRT + 0.2 ng/ml. Cox regression analysis was performed to assess the impact of clinical parameters on BRFS. Recurrence patterns after sRT were analyzed.The final cohort consisted of 273 patients; 78/273 (28.6
KW  - PSMA-PET (Other)
KW  - Prostate cancer (Other)
KW  - Prostate-specific antigen (Other)
KW  - Salvage radiotherapy (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:36905411
DO  - DOI:10.1007/s00259-023-06185-5
UR  - https://inrepo02.dkfz.de/record/274211
ER  -