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000274577 1001_ $$00000-0002-4805-0774$$aAlmanza-Aguilera, Enrique$$b0
000274577 245__ $$aCorrelation Analysis between Dietary Intake of Tyrosols and Their Food Sources and Urinary Excretion of Tyrosol and Hydroxytyrosol in a European Population.
000274577 260__ $$aBasel$$bMDPI$$c2023
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000274577 520__ $$aThis study analyzed the correlations between the acute and habitual intake of dietary tyrosols, their main food sources, and 24 h urine excretions of tyrosol (Tyr) and hydroxytyrosol (OHTyr) in participants from the European Prospective Investigation into Cancer and Nutrition study (EPIC). Participants (n = 419) were healthy men and women aged from 34 to 73 years from 8 EPIC centers belonging to France, Italy, and Germany. Acute and habitual dietary data were collected using a standardized 24 h dietary recall software and validated country-specific dietary questionnaires, respectively. The intake of 13 dietary tyrosols was estimated using the Phenol-Explorer database. Excretions of Tyr and OHTyr in a single 24 h urine sample were analyzed using tandem mass spectrometry. Urinary excretions of Tyr, OHTyr, and their sum (Tyr + OHTyr) correlated more strongly with their corresponding acute (rhopartial~0.63) rather than habitual intakes (rhopartial~0.47). In addition, individual and combined urinary excretions of Tyr and OHTyr were weakly to moderately correlated with the acute and habitual intake of other individual tyrosol precursors (rhopartial = 0.10-0.44) and especially with major food sources, such as wine (rhopartial = 0.41-0.58), olive oil (rhopartial = 0.25-0.44), and beer (rhopartial = 0.14-0.23). Urinary Tyr + OHTyr excretions were similarly correlated with the acute intake of total tyrosols but differently correlated with food sources among countries. Based on these results, we conclude that 24 h urinary excretions of Tyr + OHTyr could be proposed as biomarkers of total tyrosol intake, preferably for acute intakes.
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000274577 650_7 $$2Other$$aEPIC
000274577 650_7 $$2Other$$abiomarkers
000274577 650_7 $$2Other$$ahydroxytyrosol
000274577 650_7 $$2Other$$aolive oil
000274577 650_7 $$2Other$$atyrosol
000274577 650_7 $$2Other$$aurine
000274577 650_7 $$2Other$$awine
000274577 7001_ $$aDavila-Cordova, Estefanía$$b1
000274577 7001_ $$aGuiñón-Fort, Daniel$$b2
000274577 7001_ $$aFarràs, Marta$$b3
000274577 7001_ $$00000-0002-5758-9069$$aMasala, Giovanna$$b4
000274577 7001_ $$aSantucci de Magistris, Maria$$b5
000274577 7001_ $$00000-0002-8537-9691$$aBaldassari, Ivan$$b6
000274577 7001_ $$00000-0003-2666-414X$$aTumino, Rosario$$b7
000274577 7001_ $$aPadroni, Lisa$$b8
000274577 7001_ $$0P:(DE-He78)fb68a9386399d72d84f7f34cfc6048b4$$aKatzke, Verena A$$b9$$udkfz
000274577 7001_ $$00000-0002-0830-5277$$aSchulze, Matthias B$$b10
000274577 7001_ $$aScalbert, Augustin$$b11
000274577 7001_ $$00000-0002-6236-6804$$aZamora-Ros, Raul$$b12
000274577 773__ $$0PERI:(DE-600)2704216-9$$a10.3390/antiox12030715$$gVol. 12, no. 3, p. 715 -$$n3$$p715$$tAntioxidants$$v12$$x2076-3921$$y2023
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