%0 Journal Article
%A Martini, Alberto
%A Wever, Lieke
%A Soeterik, Timo F W
%A Rakauskas, Arnas
%A Fankhauser, Christian Daniel
%A Grogg, Josias Bastian
%A Checcucci, Enrico
%A Amparore, Daniele
%A Haiquel, Luciano
%A Rodriguez-Sanchez, Lara
%A Ploussard, Guillaume
%A Qiang, Peng
%A Affentranger, Andres
%A Marquis, Alessandro
%A Marra, Giancarlo
%A Ettala, Otto
%A Zattoni, Fabio
%A Falagario, Ugo Giovanni
%A De Angelis, Mario
%A Kesch, Claudia
%A Apfelbeck, Maria
%A Al-Hammouri, Tarek
%A Kretschmer, Alexander
%A Kasivisvanathan, Veeru
%A Preisser, Felix
%A Lefebvre, Emilie
%A Olivier, Jonathan
%A Radtke, Jan Philipp
%A Briganti, Alberto
%A Montorsi, Francesco
%A Carrieri, Giuseppe
%A Moro, Fabrizio Dal
%A Boström, Peter
%A Jambor, Ivan
%A Gontero, Paolo
%A Chiu, Peter K
%A John, Hubert
%A Macek, Petr
%A Porpiglia, Francesco
%A Hermanns, Thomas
%A van den Bergh, Roderick C N
%A van Basten, Jean-Paul A
%A Gandaglia, Giorgio
%A Valerio, Massimo
%T Unilateral Pelvic Lymph Node Dissection in Prostate Cancer Patients Diagnosed in the Era of Magnetic Resonance Imaging-targeted Biopsy: A Study That Challenges the Dogma.
%J The journal of urology
%V 210
%N 1
%@ 0022-5347
%C New York, NY [u.a.]
%I Elsevier
%M DKFZ-2023-00752
%P 117-127
%D 2023
%Z 2023 Jul;210(1):117-127
%X Bilateral extended pelvic lymph node dissection at the time of radical prostatectomy is the current standard of care if pelvic lymph node dissection is indicated; often, however, pelvic lymph node dissection is performed in pN0 disease. With the more accurate staging achieved with magnetic resonance imaging-targeted biopsies for prostate cancer diagnosis, the indication for bilateral extended pelvic lymph node dissection may be revised. We aimed to assess the feasibility of unilateral extended pelvic lymph node dissection in the era of modern prostate cancer imaging.We analyzed a multi-institutional data set of men with cN0 disease diagnosed by magnetic resonance imaging-targeted biopsy who underwent prostatectomy and bilateral extended pelvic lymph node dissection. The outcome of the study was lymph node invasion contralateral to the prostatic lobe with worse disease features, ie, dominant lobe. Logistic regression to predict lymph node invasion contralateral to the dominant lobe was generated and internally validated.Overall, data from 2,253 patients were considered. Lymph node invasion was documented in 302 (13
%K magnetic resonance imaging (Other)
%K prostatic neoplasms (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37052480
%R 10.1097/JU.0000000000003442
%U https://inrepo02.dkfz.de/record/275429