TY  - JOUR
AU  - Martini, Alberto
AU  - Wever, Lieke
AU  - Soeterik, Timo F W
AU  - Rakauskas, Arnas
AU  - Fankhauser, Christian Daniel
AU  - Grogg, Josias Bastian
AU  - Checcucci, Enrico
AU  - Amparore, Daniele
AU  - Haiquel, Luciano
AU  - Rodriguez-Sanchez, Lara
AU  - Ploussard, Guillaume
AU  - Qiang, Peng
AU  - Affentranger, Andres
AU  - Marquis, Alessandro
AU  - Marra, Giancarlo
AU  - Ettala, Otto
AU  - Zattoni, Fabio
AU  - Falagario, Ugo Giovanni
AU  - De Angelis, Mario
AU  - Kesch, Claudia
AU  - Apfelbeck, Maria
AU  - Al-Hammouri, Tarek
AU  - Kretschmer, Alexander
AU  - Kasivisvanathan, Veeru
AU  - Preisser, Felix
AU  - Lefebvre, Emilie
AU  - Olivier, Jonathan
AU  - Radtke, Jan Philipp
AU  - Briganti, Alberto
AU  - Montorsi, Francesco
AU  - Carrieri, Giuseppe
AU  - Moro, Fabrizio Dal
AU  - Boström, Peter
AU  - Jambor, Ivan
AU  - Gontero, Paolo
AU  - Chiu, Peter K
AU  - John, Hubert
AU  - Macek, Petr
AU  - Porpiglia, Francesco
AU  - Hermanns, Thomas
AU  - van den Bergh, Roderick C N
AU  - van Basten, Jean-Paul A
AU  - Gandaglia, Giorgio
AU  - Valerio, Massimo
TI  - Unilateral Pelvic Lymph Node Dissection in Prostate Cancer Patients Diagnosed in the Era of Magnetic Resonance Imaging-targeted Biopsy: A Study That Challenges the Dogma.
JO  - The journal of urology
VL  - 210
IS  - 1
SN  - 0022-5347
CY  - New York, NY [u.a.]
PB  - Elsevier
M1  - DKFZ-2023-00752
SP  - 117-127
PY  - 2023
N1  - 2023 Jul;210(1):117-127
AB  - Bilateral extended pelvic lymph node dissection at the time of radical prostatectomy is the current standard of care if pelvic lymph node dissection is indicated; often, however, pelvic lymph node dissection is performed in pN0 disease. With the more accurate staging achieved with magnetic resonance imaging-targeted biopsies for prostate cancer diagnosis, the indication for bilateral extended pelvic lymph node dissection may be revised. We aimed to assess the feasibility of unilateral extended pelvic lymph node dissection in the era of modern prostate cancer imaging.We analyzed a multi-institutional data set of men with cN0 disease diagnosed by magnetic resonance imaging-targeted biopsy who underwent prostatectomy and bilateral extended pelvic lymph node dissection. The outcome of the study was lymph node invasion contralateral to the prostatic lobe with worse disease features, ie, dominant lobe. Logistic regression to predict lymph node invasion contralateral to the dominant lobe was generated and internally validated.Overall, data from 2,253 patients were considered. Lymph node invasion was documented in 302 (13
KW  - magnetic resonance imaging (Other)
KW  - prostatic neoplasms (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37052480
DO  - DOI:10.1097/JU.0000000000003442
UR  - https://inrepo02.dkfz.de/record/275429
ER  -