TY  - JOUR
AU  - Zidane, Miriam
AU  - Theurich, Sebastian
AU  - Schlaak, Max
TI  - Malignes Melanom und Adipositas: eine Übersichtsarbeit
JO  - Tumordiagnostik & Therapie
VL  - 44
IS  - 03
SN  - 0722-219X
CY  - Stuttgart
PB  - Thieme
M1  - DKFZ-2023-00759
SP  - 202 - 210
PY  - 2023
AB  - Introduction: The incidence of obesity continues to increase worldwide. Obesity is discussed as a potential risk factor for various types of cancer including malignant melanoma. This review presents the evidence for the association between obesity and malignant melanoma.Results: Although several explanatory approaches for the association between obesity and malignant melanoma exist, these are currently not fully understood and remain subject of research. The evidence on the association between obesity and melanoma outcomes for patients without systemic therapy is low. For patients with systemic therapy existing evidence points to a protective effect of immuno- and targeted therapies.Conclusion: Overall, current evidence is insufficient to conclude whether obesity has an independent protective effect or is a risk factor for the development of malignant melanoma. Further research is needed to assess this potential association in greater depth.
LB  - PUB:(DE-HGF)16
DO  - DOI:10.1055/a-2037-1458
UR  - https://inrepo02.dkfz.de/record/275436
ER  -