%0 Journal Article
%A Zwicker, Felix
%A Klepper, Rudolf
%A Hauswald, Henrik
%A Hoefel, Sebastian
%A Raether, Luis
%A Huber, Peter E
%A Debus, Juergen
%A Schempp, Michael
%T Helical Tomotherapy of Lymph Node-negative Early-stage Breast Cancer After Breast-conserving Surgery: Long-term Results.
%J Anticancer research
%V 43
%N 5
%@ 0250-7005
%C Attiki
%M DKFZ-2023-00822
%P 2041 - 2053
%D 2023
%Z #EA:E055#
%X Adjuvant radiotherapy is an integral part of the interdisciplinary curative treatment of breast cancer. We aimed to examine the long-term clinical results of helical tomotherapy in female patients with local restricted, lymph node negative breast cancer after breast-conserving surgery.In this single-centre analysis, 219 female patients with early-stage breast cancer (T1/2) and no lymph node metastasis (N0) following breast-conserving surgery and sentinel-node biopsy were treated with adjuvant fractionated whole breast radiation therapy using helical tomotherapy. When boost irradiation was indicated, it was administered sequentially or using the simultaneous-integrated boost technique. Local control (LC), metastasis and survival rates, acute toxicity, late toxicity, and secondary malignancy rates were analysed retrospectively.The mean follow-up time was 71 months. The 5- and 8-year overall survival (OS) rates were 97.7
%K Breast cancer (Other)
%K helical IMRT (Other)
%K long-term results (Other)
%K lymph node negative (Other)
%K lymphedema (Other)
%K radiotherapy (Other)
%K secondary malignoma (Other)
%K tomotherapy (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37097694
%R 10.21873/anticanres.16365
%U https://inrepo02.dkfz.de/record/275616