TY  - JOUR
AU  - Thurner, Lorenz
AU  - Fadle, Natalie
AU  - Regitz, Evi
AU  - Roth, Sophie
AU  - Cetin, Onur
AU  - Kos, Igor Age
AU  - Hess, Simon Mauro
AU  - Bein, Julia
AU  - Bohle, Rainer Maria
AU  - Vornanen, Martine
AU  - Sundström, Christer
AU  - De Leval, Laurence
AU  - Tiacci, Enrico
AU  - Borchmann, Peter
AU  - Engert, Andreas
AU  - Poeschel, Viola
AU  - Held, Gerhard
AU  - Schwarz, Eva C
AU  - Neumann, Frank
AU  - Preuss, Klaus-Dieter
AU  - Hoth, Markus
AU  - Küppers, Ralf
AU  - Lehman, Karola
AU  - Hansmann, Martin-Leo
AU  - Becker, Sören L
AU  - Bewarder, Moritz
AU  - Hartmann, Sylvia
TI  - B-cell receptor reactivity against Rothia mucilaginosa in nodular lymphocyte-predominant Hodgkin lymphoma.
JO  - Haematologica
VL  - 108
IS  - 12
SN  - 0390-6078
CY  - Pavia
PB  - Ferrata Storti Foundation
M1  - DKFZ-2023-00874
SP  - 3347-3358
PY  - 2023
N1  - 2023 Dec 1;108(12):3347-3358
AB  - Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a Hodgkin lymphoma expressing functional B-cell receptors (BCRs). Recently, we described a dual stimulation model of IgD+ lymphocyte-predominant (LP) cells by Moraxella catarrhalis antigen RpoC and its superantigen MID/hag, associated with extralong CDR3s and HLA-DRB1*04 or HLA-DRB1*07 haplotype. Aim of the present study was to extend the antigen screening to further bacteria and viruses. Fabs of 7 new and 15 previously reported cases were analyzed. The reactivity of non-Moraxella spp.-reactive Fabs against lysates of Rothia mucilaginosa was observed in 5/22 (22.7
LB  - PUB:(DE-HGF)16
C6  - pmid:37139600
DO  - DOI:10.3324/haematol.2023.282698
UR  - https://inrepo02.dkfz.de/record/275780
ER  -