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@ARTICLE{Tichanek:275939,
      author       = {F. Tichanek and A. Försti$^*$ and O. Hemminki and A.
                      Hemminki and K. Hemminki$^*$},
      title        = {{S}urvival in {L}ung {C}ancer in the {N}ordic {C}ountries
                      {T}hrough {A} {H}alf {C}entury.},
      journal      = {Clinical epidemiology},
      volume       = {15},
      issn         = {1179-1349},
      address      = {Albany, Auckland},
      publisher    = {Dove Medical Press},
      reportid     = {DKFZ-2023-00927},
      pages        = {503 - 510},
      year         = {2023},
      note         = {#LA:C020#},
      abstract     = {Lung cancer is often diagnosed at an advanced stage and
                      survival has been poor, although long-term studies have been
                      rare. We analyzed data on survival in lung cancer from
                      Denmark, Finland, Norway, and Sweden over a 50-year period
                      (1971-2020).Relative 1- and 5-year survival data were
                      obtained from the NORDCAN database for 1971-2020. We used
                      generalized additive models to estimate survival trends over
                      time and uncertainty of these estimates. We additionally
                      calculated conditional survival from the 1st to 5th year
                      (5/1-year), estimated annual changes in survival rates, and
                      determined significant breaking points.In 2016-2020, 5-year
                      survival rate for lung cancer was best for Norwegian men
                      $(26.6\%)$ and women $(33.2\%).$ The sex difference was
                      significant and it was found for each country. Survival
                      improved modestly until the year 2000, after which time
                      survival curves increased steeply and kept the linear shape
                      to the end of follow-up, indicating consistent improvement
                      in survival. Survival curves for 1- and 5/1-year survival
                      were almost superimposable, indicating that deaths in the
                      first year were approximately as many as in the subsequent 4
                      years, thus marking sustained long-term survival.We could
                      document a positive development in lung cancer survival with
                      steep upward trends after the year 2000. Intensions for
                      curative treatment have been increasing and the outcomes
                      have been improving with the help of novel imaging methods.
                      Pathways for facile patient access to treatment have been
                      instituted. Close to $90\%$ of the patients are ever
                      smokers. National anti-smoking acts and alerting people who
                      smoke about early symptoms may be beneficial, as metastatic
                      lung cancer remains difficult to cure.},
      keywords     = {conditional survival (Other) / lung cancer (Other) /
                      relative survival (Other) / smoking (Other) / surgery
                      (Other) / treatment (Other)},
      cin          = {B062 / HD01 / C020},
      ddc          = {610},
      cid          = {I:(DE-He78)B062-20160331 / I:(DE-He78)HD01-20160331 /
                      I:(DE-He78)C020-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:37153073},
      pmc          = {pmc:PMC10162394},
      doi          = {10.2147/CLEP.S406606},
      url          = {https://inrepo02.dkfz.de/record/275939},
}