%0 Journal Article
%A John, Lukas
%A Miah, Kaya
%A Benner, Axel
%A Mai, Elias K
%A Kriegsmann, Katharina
%A Hundemer, Michael
%A Kaudewitz, Dorothee
%A Müller-Tidow, Carsten
%A Jordan, Karin
%A Goldschmidt, Hartmut
%A Raab, Marc S
%A Giesen, Nicola
%T Impact of novel agent therapies on immune cell subsets and infectious complications in patients with relapsed/refractory multiple myeloma.
%J Frontiers in oncology
%V 13
%@ 2234-943X
%C Lausanne
%I Frontiers Media
%M DKFZ-2023-00929
%P 1078725
%D 2023
%Z #EA:A360#
%X Infections are a leading cause of morbidity and mortality in patients with multiple myeloma (MM).To examine the effects of modern second-generation novel agent therapy on immune cell subsets, in particular CD4+-T-cells, and infectious complications in patients with relapsed/refractory MM (RRMM), we conducted a prospective cohort study in 112 RRMM patients.Substantially decreased CD4+-T-cells <200/µl before initiation of relapse therapy were detected in 27.7
%K CD4+-T-cells (Other)
%K immune cell subsets (Other)
%K infections (Other)
%K novel agents (Other)
%K relapsed refractory multiple myeloma (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37152008
%2 pmc:PMC10160457
%R 10.3389/fonc.2023.1078725
%U https://inrepo02.dkfz.de/record/275941