TY  - JOUR
AU  - John, Lukas
AU  - Miah, Kaya
AU  - Benner, Axel
AU  - Mai, Elias K
AU  - Kriegsmann, Katharina
AU  - Hundemer, Michael
AU  - Kaudewitz, Dorothee
AU  - Müller-Tidow, Carsten
AU  - Jordan, Karin
AU  - Goldschmidt, Hartmut
AU  - Raab, Marc S
AU  - Giesen, Nicola
TI  - Impact of novel agent therapies on immune cell subsets and infectious complications in patients with relapsed/refractory multiple myeloma.
JO  - Frontiers in oncology
VL  - 13
SN  - 2234-943X
CY  - Lausanne
PB  - Frontiers Media
M1  - DKFZ-2023-00929
SP  - 1078725
PY  - 2023
N1  - #EA:A360#
AB  - Infections are a leading cause of morbidity and mortality in patients with multiple myeloma (MM).To examine the effects of modern second-generation novel agent therapy on immune cell subsets, in particular CD4+-T-cells, and infectious complications in patients with relapsed/refractory MM (RRMM), we conducted a prospective cohort study in 112 RRMM patients.Substantially decreased CD4+-T-cells <200/µl before initiation of relapse therapy were detected in 27.7
KW  - CD4+-T-cells (Other)
KW  - immune cell subsets (Other)
KW  - infections (Other)
KW  - novel agents (Other)
KW  - relapsed refractory multiple myeloma (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37152008
C2  - pmc:PMC10160457
DO  - DOI:10.3389/fonc.2023.1078725
UR  - https://inrepo02.dkfz.de/record/275941
ER  -