TY  - JOUR
AU  - Dao Trong, Philip
AU  - Kilian, Samuel
AU  - Jesser, Jessica
AU  - Reuss, David
AU  - Aras, Fuat Kaan
AU  - von Deimling, Andreas
AU  - Herold-Mende, Christel
AU  - Unterberg, Andreas
AU  - Jungk, Christine
TI  - Risk Estimation in Non-Enhancing Glioma: Introducing a Clinical Score.
JO  - Cancers
VL  - 15
IS  - 9
SN  - 2072-6694
CY  - Basel
PB  - MDPI
M1  - DKFZ-2023-00979
SP  - 2503
PY  - 2023
AB  - The preoperative grading of non-enhancing glioma (NEG) remains challenging. Herein, we analyzed clinical and magnetic resonance imaging (MRI) features to predict malignancy in NEG according to the 2021 WHO classification and developed a clinical score, facilitating risk estimation. A discovery cohort (2012-2017, n = 72) was analyzed for MRI and clinical features (T2/FLAIR mismatch sign, subventricular zone (SVZ) involvement, tumor volume, growth rate, age, Pignatti score, and symptoms). Despite a 'low-grade' appearance on MRI, 81
KW  - CDKN2A/B (Other)
KW  - IDH mutation (Other)
KW  - lower-grade glioma (Other)
KW  - malignant glioma (Other)
KW  - molecular classification (Other)
KW  - non-enhancing glioma (Other)
KW  - prognostic score (Other)
KW  - risk estimation (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37173969
C2  - pmc:PMC10177456
DO  - DOI:10.3390/cancers15092503
UR  - https://inrepo02.dkfz.de/record/276073
ER  -