%0 Journal Article %A Gwenzi, Tafirenyika %A Zhu, Anna %A Schrotz-King, Petra %A Schöttker, Ben %A Hoffmeister, Michael %A Brenner, Hermann %T Effects of vitamin D supplementation on inflammatory response in patients with cancer and precancerous lesions: Systematic review and meta-analysis of randomized trials. %J Clinical nutrition %V 42 %N 7 %@ 0261-5614 %C Amsterdam [u.a.] %I Elsevier %M DKFZ-2023-01059 %P 1142-1150 %D 2023 %Z 2023 Jul;42(7):1142-1150 / #EA:C120#LA:C120#LA:C070# %X Inflammation plays a key role in tumor development and progression. Vitamin D has potential tumor suppressing effects through modulation of inflammatory processes. The aim of this systematic review and meta-analysis of randomized controlled trials (RCTs) was to summarize and evaluate the effects of vitamin D3 supplementation (VID3S) on serum inflammatory biomarkers among patients with cancer or pre-cancerous lesions.We searched PubMed, Web of Science and Cochrane databases until November 2022. The effects of VID3S were estimated from pooled standardized mean differences (SMDs) with their 95 %K Biomarker (Other) %K Cancer (Other) %K Inflammation (Other) %K Precancer (Other) %K Vitamin D3 supplement (Other) %F PUB:(DE-HGF)16 %9 Journal Article %$ pmid:37244755 %R 10.1016/j.clnu.2023.05.009 %U https://inrepo02.dkfz.de/record/276329