%0 Journal Article
%A Hertler, Caroline
%A Felsberg, Jörg
%A Gramatzki, Dorothee
%A Le Rhun, Emilie
%A Clarke, Jennifer
%A Soffietti, Riccardo
%A Wick, Wolfgang
%A Chinot, Olivier
%A Ducray, François
%A Roth, Patrick
%A McDonald, Kerrie
%A Hau, Peter
%A Hottinger, Andreas F
%A Reijneveld, Jaap
%A Schnell, Oliver
%A Marosi, Christine
%A Glantz, Michael
%A Darlix, Amélie
%A Lombardi, Giuseppe
%A Krex, Dietmar
%A Glas, Martin
%A Reardon, David A
%A van den Bent, Martin
%A Lefranc, Florence
%A Herrlinger, Ulrich
%A Razis, Evangelia
%A Carpentier, Antoine F
%A Phillips, Samuel
%A Rudà, Roberta
%A Wick, Antje
%A Tabouret, Emeline
%A Meyronet, David
%A Maurage, Claude-Alain
%A Rushing, Elisabeth
%A Rapkins, Robert
%A Bumes, Elisabeth
%A Hegi, Monika
%A Weyerbrock, Astrid
%A Aregawi, Dawit
%A Gonzalez-Gomez, Christian
%A Pellerino, Alessia
%A Klein, Martin
%A Preusser, Matthias
%A Bendszus, Martin
%A Golfinopoulos, Vassilis
%A von Deimling, Andreas
%A Gorlia, Thierry
%A Wen, Patrick Y
%A Reifenberger, Guido
%A Weller, Michael
%T Long-term survival with IDH wildtype glioblastoma: first results from the ETERNITY Brain Tumor Funders' Collaborative Consortium (EORTC 1419).
%J European journal of cancer
%V 189
%@ 0014-2964
%C Amsterdam [u.a.]
%I Elsevier
%M DKFZ-2023-01107
%P 112913
%D 2023
%Z Volume 189, August 2023, 112913
%X Median survival with glioblastoma remains in the range of 12 months on population levels. Only few patients survive for more than 5 years. Patient and disease features associated with long-term survival remain poorly defined.European Organization for Research and Treatment of Cancer (EORTC) 1419 (ETERNITY) is a registry study supported by the Brain Tumor Funders Collaborative in the US and the EORTC Brain Tumor Group. Patients with glioblastoma surviving at least 5 years from diagnosis were identified at 24 sites in Europe, US, and Australia. In patients with isocitrate dehydrogenase (IDH) wildtype tumours, prognostic factors were analysed using the Kaplan-Meier method and the Cox proportional hazards model. A population-based reference cohort was obtained from the Cantonal cancer registry Zurich.At the database lock of July 2020, 280 patients with histologically centrally confirmed glioblastoma (189 IDH wildtype, 80 IDH mutant, 11 incompletely characterised) had been registered. In the IDH wildtype population, median age was 56 years (range 24-78 years), 96 patients (50.8
%K IDH (Other)
%K MGMT (Other)
%K Outcome (Other)
%K Prognosis (Other)
%K Registry (Other)
%K Wildtype (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37277265
%R 10.1016/j.ejca.2023.05.002
%U https://inrepo02.dkfz.de/record/276424