%0 Journal Article
%A Seidensaal, Katharina
%A Dostal, Matthias
%A Kudak, Andreas
%A Jaekel, Cornelia
%A Meixner, Eva
%A Liermann, Jakob
%A Weykamp, Fabian
%A Hoegen, Philipp
%A Mechtersheimer, Gunhild
%A Willis, Franziska
%A Schneider, Martin
%A Debus, Jürgen
%T Preoperative Dose-Escalated Intensity-Modulated Radiotherapy (IMRT) and Intraoperative Radiation Therapy (IORT) in Patients with Retroperitoneal Soft-Tissue Sarcoma: Final Results of a Clinical Phase I/II Trial
%J Cancers
%V 15
%N 10
%@ 2072-6694
%C Basel
%I MDPI
%M DKFZ-2023-01130
%P 2747
%D 2023
%Z #LA:E050#
%X Background: To report the final results of a prospective, one-armed, single-center phase I/II trial (NCT01566123). Methods: Between 2007 and 2017, 37 patients with primary or recurrent (N = 6) retroperitoneal sarcomas were enrolled. Treatment included preoperative IMRT of 45–50 Gy with a simultaneous integrated boost of 50–56 Gy, surgery and IORT. The primary endpoint was local control (LC) at 5 years. The most common histology was dedifferentiated liposarcoma (51
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37345084
%R 10.3390/cancers15102747
%U https://inrepo02.dkfz.de/record/276749