TY  - JOUR
AU  - Seidensaal, Katharina
AU  - Dostal, Matthias
AU  - Kudak, Andreas
AU  - Jaekel, Cornelia
AU  - Meixner, Eva
AU  - Liermann, Jakob
AU  - Weykamp, Fabian
AU  - Hoegen, Philipp
AU  - Mechtersheimer, Gunhild
AU  - Willis, Franziska
AU  - Schneider, Martin
AU  - Debus, Jürgen
TI  - Preoperative Dose-Escalated Intensity-Modulated Radiotherapy (IMRT) and Intraoperative Radiation Therapy (IORT) in Patients with Retroperitoneal Soft-Tissue Sarcoma: Final Results of a Clinical Phase I/II Trial
JO  - Cancers
VL  - 15
IS  - 10
SN  - 2072-6694
CY  - Basel
PB  - MDPI
M1  - DKFZ-2023-01130
SP  - 2747
PY  - 2023
N1  - #LA:E050#
AB  - Background: To report the final results of a prospective, one-armed, single-center phase I/II trial (NCT01566123). Methods: Between 2007 and 2017, 37 patients with primary or recurrent (N = 6) retroperitoneal sarcomas were enrolled. Treatment included preoperative IMRT of 45–50 Gy with a simultaneous integrated boost of 50–56 Gy, surgery and IORT. The primary endpoint was local control (LC) at 5 years. The most common histology was dedifferentiated liposarcoma (51
LB  - PUB:(DE-HGF)16
C6  - pmid:37345084
DO  - DOI:10.3390/cancers15102747
UR  - https://inrepo02.dkfz.de/record/276749
ER  -