%0 Journal Article
%A Zaun, Gregor
%A Weber, Manuel
%A Metzenmacher, Martin
%A Wiesweg, Marcel
%A Hilser, Thomas
%A Zaun, Yasmin
%A Liffers, Sven
%A Pogorzelski, Michael
%A Virchow, Isabel
%A Eberhardt, Wilfried
%A Theurer, Sarah
%A Sabbah, Tanja Abu
%A Reissig, Timm M
%A Stuschke, Martin
%A Kürten, Cornelius
%A Hussain, Timon
%A Lang, Stephan
%A Kasper, Stefan
%A Fendler, Wolfgang
%A Herrmann, Ken
%A Schuler, Martin
%T SUVmax Above 20 in 18F-FDG PET/CT at Initial Diagnostic Workup Associates with Favorable Survival in Patients with Cancer of Unknown Primary.
%J Journal of nuclear medicine
%V 64
%N 8
%@ 0097-9058
%C New York, NY
%I Soc.
%M DKFZ-2023-01186
%P 1191-1194
%D 2023
%Z 2023 Aug;64(8):1191-1194
%X Cancer of unknown primary (CUP) is a heterogeneous entity with a limited prognosis. Novel prognostic markers are needed for patient stratification in prospective clinical trials exploring innovative therapies. Methods: In CUP patients treated at the West German Cancer Center Essen, the prognostic value of 18F-FDG PET/CT at the initial diagnostic workup was analyzed by comparing overall survival (OS) in patients who underwent 18F-FDG PET/CT with those who did not. Results: Of 154 patients with a CUP diagnosis, 76 underwent 18F-FDG PET/CT at the initial diagnostic workup. The median overall survival (OS) of the full analysis set was 20.0 mo. Within the PET/CT subgroup, an SUVmax above 20 was associated with significantly superior OS (median OS, not reached vs. 32.0 mo; hazard ratio, 0.261; 95
%K 18F-FDG PET/CT (Other)
%K CUP (Other)
%K SUVmax (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37321823
%R 10.2967/jnumed.122.265161
%U https://inrepo02.dkfz.de/record/276877