TY  - JOUR
AU  - Zaun, Gregor
AU  - Weber, Manuel
AU  - Metzenmacher, Martin
AU  - Wiesweg, Marcel
AU  - Hilser, Thomas
AU  - Zaun, Yasmin
AU  - Liffers, Sven
AU  - Pogorzelski, Michael
AU  - Virchow, Isabel
AU  - Eberhardt, Wilfried
AU  - Theurer, Sarah
AU  - Sabbah, Tanja Abu
AU  - Reissig, Timm M
AU  - Stuschke, Martin
AU  - Kürten, Cornelius
AU  - Hussain, Timon
AU  - Lang, Stephan
AU  - Kasper, Stefan
AU  - Fendler, Wolfgang
AU  - Herrmann, Ken
AU  - Schuler, Martin
TI  - SUVmax Above 20 in 18F-FDG PET/CT at Initial Diagnostic Workup Associates with Favorable Survival in Patients with Cancer of Unknown Primary.
JO  - Journal of nuclear medicine
VL  - 64
IS  - 8
SN  - 0097-9058
CY  - New York, NY
PB  - Soc.
M1  - DKFZ-2023-01186
SP  - 1191-1194
PY  - 2023
N1  - 2023 Aug;64(8):1191-1194
AB  - Cancer of unknown primary (CUP) is a heterogeneous entity with a limited prognosis. Novel prognostic markers are needed for patient stratification in prospective clinical trials exploring innovative therapies. Methods: In CUP patients treated at the West German Cancer Center Essen, the prognostic value of 18F-FDG PET/CT at the initial diagnostic workup was analyzed by comparing overall survival (OS) in patients who underwent 18F-FDG PET/CT with those who did not. Results: Of 154 patients with a CUP diagnosis, 76 underwent 18F-FDG PET/CT at the initial diagnostic workup. The median overall survival (OS) of the full analysis set was 20.0 mo. Within the PET/CT subgroup, an SUVmax above 20 was associated with significantly superior OS (median OS, not reached vs. 32.0 mo; hazard ratio, 0.261; 95
KW  - 18F-FDG PET/CT (Other)
KW  - CUP (Other)
KW  - SUVmax (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37321823
DO  - DOI:10.2967/jnumed.122.265161
UR  - https://inrepo02.dkfz.de/record/276877
ER  -