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@ARTICLE{Koschig:276911,
      author       = {M. Koschig and I. Conrad and K. Berger and B. T. Baune and
                      H. J. Grabe and D. Gerstorf and C. Meinke-Franze and H.
                      Völzke and R. Mikolajczyk and M. Leitzmann and J. Fricke
                      and T. Keil and L. Koch-Gallenkamp$^*$ and L. Perna and N.
                      Obi and A. Pabst and S. G. Riedel-Heller},
      title        = {{T}he mediating role of personality traits in the
                      association between childhood trauma and depressive symptoms
                      in young adulthood.},
      journal      = {Journal of affective disorders},
      volume       = {338},
      issn         = {0165-0327},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {DKFZ-2023-01204},
      pages        = {373-379},
      year         = {2023},
      note         = {2023 Oct 1;338:373-379},
      abstract     = {The aim of this study was to investigate the mediating role
                      of the Big 5 personality traits (extraversion, neuroticism,
                      openness, agreeableness, conscientiousness) in the
                      association between early traumatization and depressive
                      symptoms in early adulthood (20-25-year-olds) in a German
                      population-based sample.A total of 3176 participants from
                      the German National Cohort (NAKO) baseline with an age
                      between 20 and 25 years were included in this investigation.
                      The sum score of the 9-item-version of the Patient Health
                      Questionnaire was used for assessment of depressive
                      symptoms. A structural equation model was built to test the
                      paths between childhood trauma, Big 5 personality traits and
                      depressive symptoms.Overall, 10.7 $\%$ of the young adult
                      sample had a PHQ-9 sum score of ten or higher. The final
                      mediation model fitted well for young adults. We found
                      evidence for a partial mediating effect of Big 5 personality
                      traits.We only adjusted for age, sex, and year of data
                      collection and did not include biological factors in the
                      model.Young adults with early trauma experiences have a risk
                      for developing depressive symptoms in young adulthood.
                      Personality traits, especially neuroticism, partially
                      mediated the association between early trauma and depressive
                      symptoms for young adults and should be recognized in
                      preventive strategies.},
      keywords     = {Adolescent (Other) / Adverse childhood experiences (Other)
                      / Depression (Other) / Germany (Other) / Risk factors
                      (Other) / Structural equation modelling (Other)},
      cin          = {C070},
      ddc          = {610},
      cid          = {I:(DE-He78)C070-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:37331380},
      doi          = {10.1016/j.jad.2023.06.027},
      url          = {https://inrepo02.dkfz.de/record/276911},
}