TY - JOUR
AU - Christakoudi, Sofia
AU - Tsilidis, Konstantinos K
AU - Dossus, Laure
AU - Rinaldi, Sabina
AU - Weiderpass, Elisabete
AU - Antoniussen, Christian S
AU - Dahm, Christina C
AU - Tjønneland, Anne
AU - Mellemkjær, Lene
AU - Katzke, Verena
AU - Kaaks, Rudolf
AU - Schulze, Matthias B
AU - Masala, Giovanna
AU - Grioni, Sara
AU - Panico, Salvatore
AU - Tumino, Rosario
AU - Sacerdote, Carlotta
AU - May, Anne M
AU - Monninkhof, Evelyn M
AU - Quirós, J Ramón
AU - Bonet, Catalina
AU - Sánchez, Maria-Jose
AU - Amiano, Pilar
AU - Chirlaque, María-Dolores
AU - Guevara, Marcela
AU - Rosendahl, Ann H
AU - Stocks, Tanja
AU - Perez-Cornago, Aurora
AU - Tin Tin, Sandar
AU - Heath, Alicia K
AU - Aglago, Elom K
AU - Peruchet-Noray, Laia
AU - Freisling, Heinz
AU - Riboli, Elio
TI - A body shape index (ABSI) is associated inversely with post-menopausal progesterone-receptor-negative breast cancer risk in a large European cohort.
JO - BMC cancer
VL - 23
IS - 1
SN - 1471-2407
CY - Heidelberg
PB - Springer
M1 - DKFZ-2023-01215
SP - 562
PY - 2023
AB - Associations of body shape with breast cancer risk, independent of body size, are unclear because waist and hip circumferences are correlated strongly positively with body mass index (BMI).We evaluated body shape with the allometric 'a body shape index' (ABSI) and hip index (HI), which compare waist and hip circumferences, correspondingly, among individuals with the same weight and height. We examined associations of ABSI, HI, and BMI (per one standard deviation increment) with breast cancer overall, and according to menopausal status at baseline, age at diagnosis, and oestrogen and progesterone receptor status (ER+/-PR+/-) in multivariable Cox proportional hazards models using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.During a mean follow-up of 14.0 years, 9011 incident breast cancers were diagnosed among 218,276 women. Although there was little evidence for association of ABSI with breast cancer overall (hazard ratio HR = 0.984; 95
KW - Female
KW - Humans
KW - Middle Aged
KW - Body Mass Index
KW - Breast Neoplasms: complications
KW - Risk Factors
KW - Progesterone
KW - Prospective Studies
KW - Triple Negative Breast Neoplasms: complications
KW - Postmenopause
KW - Somatotypes
KW - ABSI (Other)
KW - Body shape (Other)
KW - Breast cancer (Other)
KW - Hip size (Other)
KW - Obesity (Other)
KW - Waist size (Other)
KW - Progesterone (NLM Chemicals)
LB - PUB:(DE-HGF)16
C6 - pmid:37337133
DO - DOI:10.1186/s12885-023-11056-1
UR - https://inrepo02.dkfz.de/record/276938
ER -