000276942 001__ 276942
000276942 005__ 20240229155008.0
000276942 0247_ $$2doi$$a10.1088/1361-6560/acdfb0
000276942 0247_ $$2pmid$$apmid:37336242
000276942 0247_ $$2ISSN$$a0031-9155
000276942 0247_ $$2ISSN$$a1361-6560
000276942 037__ $$aDKFZ-2023-01219
000276942 041__ $$aEnglish
000276942 082__ $$a530
000276942 1001_ $$00000-0002-6894-381X$$aChristensen, Jeppe Brage$$b0
000276942 245__ $$aOptically stimulated luminescence detectors for dosimetry and LET measurements in light ion beams.
000276942 260__ $$aBristol$$bIOP Publ.$$c2023
000276942 3367_ $$2DRIVER$$aarticle
000276942 3367_ $$2DataCite$$aOutput Types/Journal article
000276942 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1690463179_31844
000276942 3367_ $$2BibTeX$$aARTICLE
000276942 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000276942 3367_ $$00$$2EndNote$$aJournal Article
000276942 500__ $$aPhys. Med. Biol. 68 (2023) 155001
000276942 520__ $$aObjective: This work investigates the use of Al2O3:C and Al2O3:C,Mg optically stimulated luminescence (OSL) detectors to determine both the dose and the radiation quality in light ion beams. The radiation quality is here expressed through either the linear energy transfer (LET) or the closely related metric Qeff, which depends on the particle's speed and effective charge. The derived LET and Qeffvalues are applied to improve the dosimetry in light ion beams.

Approach: OSL detectors were irradiated in mono-energetic1H-,4He-,12C-, and16O-ion beams. The OSL signal is associated with two emission bands that were separated using a pulsed stimulation technique and subjected to automatic corrections based on reference irradiations. Each emission band was investigated independently for dosimetry, and the ratio of the two emission intensities was parameterized as a function of fluence- and dose-averaged LET, as well as Qeff. The determined radiation quality was subsequently applied to correct the dose for ionization quenching.

Main results: For both materials, the Qeffdeterminations in1H- and4He-ion beams are within 5 % of the Monte Carlo simulated values. Using the determined radiation quality metrics to correct the non-linear (ionization quenched) detector response leads to doses within 2 % of the reference doses. 

Significance: Al2O3:C and Al2O3:C,Mg OSL detectors are applicable for dosimetry and radiation quality estimations in1H- and4He-ions. Only Al2O3:C,Mg shows promising results for dosimetry in12C-ions. Across both materials and the investigated ions, the estimated Qeffvalues were less sensitive to the ion type than the estimated LET values. The reduced uncertainties suggest new possibilities for simultaneously estimating the physical and biological dose in particle therapy with OSL detectors.&#xD.
000276942 536__ $$0G:(DE-HGF)POF4-315$$a315 - Bildgebung und Radioonkologie (POF4-315)$$cPOF4-315$$fPOF IV$$x0
000276942 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo02.dkfz.de
000276942 650_7 $$2Other$$aionization quenching
000276942 650_7 $$2Other$$alinear energy transfer (LET)
000276942 650_7 $$2Other$$aoptically stimulated luminescence (OSL)
000276942 650_7 $$2Other$$aparticle dosimetry
000276942 650_7 $$2Other$$aparticle therapy
000276942 7001_ $$aMuñoz, Iván Domingo$$b1
000276942 7001_ $$00000-0002-4160-1078$$aBassler, Niels$$b2
000276942 7001_ $$0P:(DE-He78)5d3fd2061719ec17ba3c894c81dbde89$$aStengl, Christina$$b3$$udkfz
000276942 7001_ $$aBossin, Lily$$b4
000276942 7001_ $$aTogno, Michele$$b5
000276942 7001_ $$aSafai, Sairos$$b6
000276942 7001_ $$00000-0002-6056-9747$$aJaekel, Oliver$$b7
000276942 7001_ $$aYukihara, Eduardo G$$b8
000276942 773__ $$0PERI:(DE-600)1473501-5$$a10.1088/1361-6560/acdfb0$$p155001$$tPhysics in medicine and biology$$v68$$x0031-9155$$y2023
000276942 909CO $$ooai:inrepo02.dkfz.de:276942$$pVDB
000276942 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)5d3fd2061719ec17ba3c894c81dbde89$$aDeutsches Krebsforschungszentrum$$b3$$kDKFZ
000276942 9131_ $$0G:(DE-HGF)POF4-315$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vBildgebung und Radioonkologie$$x0
000276942 9141_ $$y2023
000276942 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2022-11-17
000276942 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2022-11-17
000276942 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2022-11-17
000276942 915__ $$0StatID:(DE-HGF)0430$$2StatID$$aNational-Konsortium$$d2023-08-26$$wger
000276942 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-08-26
000276942 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2023-08-26
000276942 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2023-08-26
000276942 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2023-08-26
000276942 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2023-08-26
000276942 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bPHYS MED BIOL : 2022$$d2023-08-26
000276942 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-08-26
000276942 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2023-08-26
000276942 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2023-08-26
000276942 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2023-08-26
000276942 9201_ $$0I:(DE-He78)E040-20160331$$kE040$$lE040 Med. Physik in der Strahlentherapie$$x0
000276942 980__ $$ajournal
000276942 980__ $$aVDB
000276942 980__ $$aI:(DE-He78)E040-20160331
000276942 980__ $$aUNRESTRICTED