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@ARTICLE{Christensen:276942,
      author       = {J. B. Christensen and I. D. Muñoz and N. Bassler and C.
                      Stengl$^*$ and L. Bossin and M. Togno and S. Safai and O.
                      Jaekel and E. G. Yukihara},
      title        = {{O}ptically stimulated luminescence detectors for dosimetry
                      and {LET} measurements in light ion beams.},
      journal      = {Physics in medicine and biology},
      volume       = {68},
      issn         = {0031-9155},
      address      = {Bristol},
      publisher    = {IOP Publ.},
      reportid     = {DKFZ-2023-01219},
      pages        = {155001},
      year         = {2023},
      note         = {Phys. Med. Biol. 68 (2023) 155001},
      abstract     = {Objective: This work investigates the use of Al2O3:C and
                      Al2O3:C,Mg optically stimulated luminescence (OSL) detectors
                      to determine both the dose and the radiation quality in
                      light ion beams. The radiation quality is here expressed
                      through either the linear energy transfer (LET) or the
                      closely related metric Qeff, which depends on the particle's
                      speed and effective charge. The derived LET and Qeffvalues
                      are applied to improve the dosimetry in light ion
                      $beams.\
\
Approach:$ OSL detectors were irradiated
                      in mono-energetic1H-,4He-,12C-, and16O-ion beams. The OSL
                      signal is associated with two emission bands that were
                      separated using a pulsed stimulation technique and subjected
                      to automatic corrections based on reference irradiations.
                      Each emission band was investigated independently for
                      dosimetry, and the ratio of the two emission intensities was
                      parameterized as a function of fluence- and dose-averaged
                      LET, as well as Qeff. The determined radiation quality was
                      subsequently applied to correct the dose for ionization
                      $quenching.\
\
Main$ results: For both materials,
                      the Qeffdeterminations in1H- and4He-ion beams are within 5
                      $\%$ of the Monte Carlo simulated values. Using the
                      determined radiation quality metrics to correct the
                      non-linear (ionization quenched) detector response leads to
                      doses within 2 $\%$ of the reference doses.
                      $\
\
Significance:$ Al2O3:C and Al2O3:C,Mg OSL
                      detectors are applicable for dosimetry and radiation quality
                      estimations in1H- and4He-ions. Only Al2O3:C,Mg shows
                      promising results for dosimetry in12C-ions. Across both
                      materials and the investigated ions, the estimated
                      Qeffvalues were less sensitive to the ion type than the
                      estimated LET values. The reduced uncertainties suggest new
                      possibilities for simultaneously estimating the physical and
                      biological dose in particle therapy with OSL
                      $detectors.\&#xD.$},
      keywords     = {ionization quenching (Other) / linear energy transfer (LET)
                      (Other) / optically stimulated luminescence (OSL) (Other) /
                      particle dosimetry (Other) / particle therapy (Other)},
      cin          = {E040},
      ddc          = {530},
      cid          = {I:(DE-He78)E040-20160331},
      pnm          = {315 - Bildgebung und Radioonkologie (POF4-315)},
      pid          = {G:(DE-HGF)POF4-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:37336242},
      doi          = {10.1088/1361-6560/acdfb0},
      url          = {https://inrepo02.dkfz.de/record/276942},
}