%0 Journal Article
%A Decker, Nina Sophia
%A Johnson, Theron
%A Behrens, Sabine
%A Obi, Nadia
%A Kaaks, Rudolf
%A Chang-Claude, Jenny
%A Turzanski-Fortner, Renée
%T Endogenous estrogen receptor modulating oxysterols and breast cancer prognosis: Results from the MARIE patient cohort.
%J British journal of cancer
%V 129
%N 3
%@ 0007-0920
%C Edinburgh
%I Nature Publ. Group
%M DKFZ-2023-01271
%P 492-502
%D 2023
%Z #EA:C020#LA:C020# / 2023 Aug;129(3):492-502
%X 27-hydroxycholesterol (HC) and 25-HC were identified as endogenous selective estrogen receptor modulators (SERMs) and estrogen receptor (ER) modulators, respectively. They are hypothesized to play a role in multiple physiologic processes and pathologies, including breast cancer development and progression.We evaluated circulating 27-HC and 25-HC, and outcomes following a breast cancer diagnosis in 2282 women from the MARIE study over median follow-up of 11.6 years. 27-HC and 25-HC were quantified by liquid chromatography-mass spectrometry. We calculated hazard ratios (HR) and 95
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37355720
%R 10.1038/s41416-023-02315-w
%U https://inrepo02.dkfz.de/record/277106