TY  - JOUR
AU  - Decker, Nina Sophia
AU  - Johnson, Theron
AU  - Behrens, Sabine
AU  - Obi, Nadia
AU  - Kaaks, Rudolf
AU  - Chang-Claude, Jenny
AU  - Turzanski-Fortner, Renée
TI  - Endogenous estrogen receptor modulating oxysterols and breast cancer prognosis: Results from the MARIE patient cohort.
JO  - British journal of cancer
VL  - 129
IS  - 3
SN  - 0007-0920
CY  - Edinburgh
PB  - Nature Publ. Group
M1  - DKFZ-2023-01271
SP  - 492-502
PY  - 2023
N1  - #EA:C020#LA:C020# / 2023 Aug;129(3):492-502
AB  - 27-hydroxycholesterol (HC) and 25-HC were identified as endogenous selective estrogen receptor modulators (SERMs) and estrogen receptor (ER) modulators, respectively. They are hypothesized to play a role in multiple physiologic processes and pathologies, including breast cancer development and progression.We evaluated circulating 27-HC and 25-HC, and outcomes following a breast cancer diagnosis in 2282 women from the MARIE study over median follow-up of 11.6 years. 27-HC and 25-HC were quantified by liquid chromatography-mass spectrometry. We calculated hazard ratios (HR) and 95
LB  - PUB:(DE-HGF)16
C6  - pmid:37355720
DO  - DOI:10.1038/s41416-023-02315-w
UR  - https://inrepo02.dkfz.de/record/277106
ER  -