000277297 001__ 277297
000277297 005__ 20240229155013.0
000277297 0247_ $$2doi$$a10.1007/s10654-023-01022-3
000277297 0247_ $$2pmid$$apmid:37386255
000277297 0247_ $$2ISSN$$a0393-2990
000277297 0247_ $$2ISSN$$a1573-7284
000277297 0247_ $$2altmetric$$aaltmetric:150745066
000277297 037__ $$aDKFZ-2023-01326
000277297 041__ $$aEnglish
000277297 082__ $$a610
000277297 1001_ $$aDi Castelnuovo, Augusto$$b0
000277297 245__ $$aDrinking alcohol in moderation is associated with lower rate of all-cause mortality in individuals with higher rather than lower educational level: findings from the MORGAM project.
000277297 260__ $$aDordrecht [u.a.]$$bSpringer Science + Business Media B.V.$$c2023
000277297 3367_ $$2DRIVER$$aarticle
000277297 3367_ $$2DataCite$$aOutput Types/Journal article
000277297 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1692081660_20940
000277297 3367_ $$2BibTeX$$aARTICLE
000277297 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000277297 3367_ $$00$$2EndNote$$aJournal Article
000277297 500__ $$a2023 Aug;38(8):869-881
000277297 520__ $$aThe association between socioeconomic status (SES) and alcohol-related diseases has been widely explored. Less is known, however, on whether the association of moderate drinking with all-cause mortality is modified by educational level (EL). Using harmonized data from 16 cohorts in the MORGAM Project (N = 142,066) the association of pattern of alcohol intake with hazard of all-cause mortality across EL (lower = primary-school; middle = secondary-school; higher = university/college degree) was assessed using multivariable Cox-regression and spline curves. A total of 16,695 deaths occurred in 11.8 years (median). In comparison with life-long abstainers, participants drinking 0.1-10 g/d of ethanol had 13% (HR = 0.87; 95%CI: 0.74-1.02), 11% (HR = 0.89; 0.84-0.95) and 5% (HR = 0.95; 0.89-1.02) lower rate of death in higher, middle and lower EL, respectively. Conversely, drinkers > 20 g/d had 1% (HR = 1.01; 0.82-1.25), 10% (HR = 1.10; 1.02-1.19) and 17% (HR = 1.17; 1.09-1.26) higher rate of death. The association of alcohol consumption with all-cause mortality was nonlinear, with a different J-shape by EL levels. It was consistent across both sexes and in various approaches of measuring alcohol consumption, including combining quantity and frequency and it was more evident when the beverage of preference was wine. We observed that drinking in moderation (≤ 10 g/d) is associated with lower mortality rate more evidently in individuals with higher EL than in people with lower EL, while heavy drinking is associated with higher mortality rate more evidently in individuals with lower EL than in people with higher EL, suggesting that advice on reducing alcohol intake should especially target individuals of low EL.
000277297 536__ $$0G:(DE-HGF)POF4-313$$a313 - Krebsrisikofaktoren und Prävention (POF4-313)$$cPOF4-313$$fPOF IV$$x0
000277297 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo02.dkfz.de
000277297 650_7 $$2Other$$aAlcohol
000277297 650_7 $$2Other$$aAll-cause mortality
000277297 650_7 $$2Other$$aEducational levels
000277297 650_7 $$2Other$$aSocial status
000277297 7001_ $$aBonaccio, Marialaura$$b1
000277297 7001_ $$aCostanzo, Simona$$b2
000277297 7001_ $$aMcElduff, Patrick$$b3
000277297 7001_ $$aLinneberg, Allen$$b4
000277297 7001_ $$aSalomaa, Veikko$$b5
000277297 7001_ $$aMännistö, Satu$$b6
000277297 7001_ $$aFerrières, Jean$$b7
000277297 7001_ $$aDallongeville, Jean$$b8
000277297 7001_ $$aThorand, Barbara$$b9
000277297 7001_ $$0P:(DE-He78)90d5535ff896e70eed81f4a4f6f22ae2$$aBrenner, Hermann$$b10$$udkfz
000277297 7001_ $$aFerrario, Marco$$b11
000277297 7001_ $$aVeronesi, Giovanni$$b12
000277297 7001_ $$aTamosiunas, Abdonas$$b13
000277297 7001_ $$aGrimsgaard, Sameline$$b14
000277297 7001_ $$aDrygas, Wojciech$$b15
000277297 7001_ $$aMalyutina, Sofia$$b16
000277297 7001_ $$aSöderberg, Stefan$$b17
000277297 7001_ $$aNordendahl, Maria$$b18
000277297 7001_ $$aKee, Frank$$b19
000277297 7001_ $$aGrassi, Guido$$b20
000277297 7001_ $$aDabboura, Salim$$b21
000277297 7001_ $$aBorchini, Rossana$$b22
000277297 7001_ $$aWestermann, Dirk$$b23
000277297 7001_ $$aSchrage, Benedikt$$b24
000277297 7001_ $$aZeller, Tanja$$b25
000277297 7001_ $$aKuulasmaa, Kari$$b26
000277297 7001_ $$aBlankenberg, Stefan$$b27
000277297 7001_ $$aDonati, Maria Benedetta$$b28
000277297 7001_ $$00000-0003-0514-5885$$aIacoviello, Licia$$b29
000277297 7001_ $$aInvestigators, MORGAM Study$$b30$$eCollaboration Author
000277297 7001_ $$ade Gaetano, Giovanni$$b31
000277297 773__ $$0PERI:(DE-600)2004992-4$$a10.1007/s10654-023-01022-3$$n8$$p869-881$$tEuropean journal of epidemiology$$v38$$x0393-2990$$y2023
000277297 909CO $$ooai:inrepo02.dkfz.de:277297$$pVDB
000277297 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)90d5535ff896e70eed81f4a4f6f22ae2$$aDeutsches Krebsforschungszentrum$$b10$$kDKFZ
000277297 9131_ $$0G:(DE-HGF)POF4-313$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vKrebsrisikofaktoren und Prävention$$x0
000277297 9141_ $$y2023
000277297 915__ $$0StatID:(DE-HGF)3002$$2StatID$$aDEAL Springer$$d2022-11-17$$wger
000277297 915__ $$0StatID:(DE-HGF)3002$$2StatID$$aDEAL Springer$$d2022-11-17$$wger
000277297 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2022-11-17
000277297 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2022-11-17
000277297 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2022-11-17
000277297 915__ $$0StatID:(DE-HGF)0430$$2StatID$$aNational-Konsortium$$d2023-08-25$$wger
000277297 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bEUR J EPIDEMIOL : 2022$$d2023-08-25
000277297 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-08-25
000277297 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-08-25
000277297 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2023-08-25
000277297 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2023-08-25
000277297 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2023-08-25
000277297 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2023-08-25
000277297 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2023-08-25
000277297 915__ $$0StatID:(DE-HGF)9910$$2StatID$$aIF >= 10$$bEUR J EPIDEMIOL : 2022$$d2023-08-25
000277297 9201_ $$0I:(DE-He78)C070-20160331$$kC070$$lC070 Klinische Epidemiologie und Alternf.$$x0
000277297 9201_ $$0I:(DE-He78)C120-20160331$$kC120$$lPräventive Onkologie$$x1
000277297 980__ $$ajournal
000277297 980__ $$aVDB
000277297 980__ $$aI:(DE-He78)C070-20160331
000277297 980__ $$aI:(DE-He78)C120-20160331
000277297 980__ $$aUNRESTRICTED