%0 Journal Article
%A Morawitz, Janna
%A Bruckmann, Nils-Martin
%A Jannusch, Kai
%A Dietzel, Frederic
%A Milosevic, Aleksandar
%A Bittner, Ann-Kathrin
%A Hoffmann, Oliver
%A Mohrmann, Svjetlana
%A Ruckhäberle, Eugen
%A Häberle, Lena
%A Fendler, Wolfgang Peter
%A Herrmann, Ken
%A Giesel, Frederik Lars
%A Antoch, Gerald
%A Umutlu, Lale
%A Kowall, Bernd
%A Stang, Andreas
%A Kirchner, Julian
%T Conventional Imaging, MRI and 18F-FDG PET/MRI for N and M Staging in Patients with Newly Diagnosed Breast Cancer.
%J Cancers
%V 15
%N 14
%@ 2072-6694
%C Basel
%I MDPI
%M DKFZ-2023-01546
%P 3646
%D 2023
%X Background: This study compares the diagnostic potential of conventional staging (computed tomography (CT), axillary sonography and bone scintigraphy), whole-body magnetic resonance imaging (MRI) and whole-body 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET/)MRI for N and M staging in newly diagnosed breast cancer. Methods: A total of 208 patients with newly diagnosed breast cancer were prospectively included in this study and underwent contrast-enhanced thoracoabdominal CT, bone scintigraphy and axillary sonography as well as contrast-enhanced whole-body 18F-FDG PET/MRI. The datasets were analyzed with respect to lesion localization and characterization. Histopathology and follow-up imaging served as the reference standard. A McNemar test was used to compare the diagnostic performance of conventional staging, MRI and 18F-FDG PET/MRI and a Wilcoxon test was used to compare differences in true positive findings for nodal staging. Results: Conventional staging determined the N stage with a sensitivity of 80.9
%K 18F-FDG PET/MRI (Other)
%K breast cancer (Other)
%K metastases (Other)
%K staging (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37509307
%2 pmc:PMC10377867
%R 10.3390/cancers15143646
%U https://inrepo02.dkfz.de/record/277878