TY  - JOUR
AU  - Morawitz, Janna
AU  - Bruckmann, Nils-Martin
AU  - Jannusch, Kai
AU  - Dietzel, Frederic
AU  - Milosevic, Aleksandar
AU  - Bittner, Ann-Kathrin
AU  - Hoffmann, Oliver
AU  - Mohrmann, Svjetlana
AU  - Ruckhäberle, Eugen
AU  - Häberle, Lena
AU  - Fendler, Wolfgang Peter
AU  - Herrmann, Ken
AU  - Giesel, Frederik Lars
AU  - Antoch, Gerald
AU  - Umutlu, Lale
AU  - Kowall, Bernd
AU  - Stang, Andreas
AU  - Kirchner, Julian
TI  - Conventional Imaging, MRI and 18F-FDG PET/MRI for N and M Staging in Patients with Newly Diagnosed Breast Cancer.
JO  - Cancers
VL  - 15
IS  - 14
SN  - 2072-6694
CY  - Basel
PB  - MDPI
M1  - DKFZ-2023-01546
SP  - 3646
PY  - 2023
AB  - Background: This study compares the diagnostic potential of conventional staging (computed tomography (CT), axillary sonography and bone scintigraphy), whole-body magnetic resonance imaging (MRI) and whole-body 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET/)MRI for N and M staging in newly diagnosed breast cancer. Methods: A total of 208 patients with newly diagnosed breast cancer were prospectively included in this study and underwent contrast-enhanced thoracoabdominal CT, bone scintigraphy and axillary sonography as well as contrast-enhanced whole-body 18F-FDG PET/MRI. The datasets were analyzed with respect to lesion localization and characterization. Histopathology and follow-up imaging served as the reference standard. A McNemar test was used to compare the diagnostic performance of conventional staging, MRI and 18F-FDG PET/MRI and a Wilcoxon test was used to compare differences in true positive findings for nodal staging. Results: Conventional staging determined the N stage with a sensitivity of 80.9
KW  - 18F-FDG PET/MRI (Other)
KW  - breast cancer (Other)
KW  - metastases (Other)
KW  - staging (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37509307
C2  - pmc:PMC10377867
DO  - DOI:10.3390/cancers15143646
UR  - https://inrepo02.dkfz.de/record/277878
ER  -