TY  - JOUR
AU  - Fleischhauer, Katharina
AU  - Tran, Thuong Hien
AU  - Meisel, Roland
AU  - Mytilineos, Joannis
AU  - Dreger, Peter
AU  - Kröger, Nicolaus
TI  - Donor Selection for Allogeneic Hematopoietic Cell Transplantation.
JO  - Deutsches Ärzteblatt international
VL  - 120
IS  - 15
SN  - 1866-0452
CY  - Köln
PB  - Dt. Ärzte-Verl.
M1  - DKFZ-2023-01552
SP  - 261-268
PY  - 2023
AB  - In Germany, each year over 3000 patients with malignant and non-malignant hematologic and systemic diseases are treated by allo - geneic hematopoietic cell transplantation (HCT). Genetic donor-recipient disparities, especially those concerning variable human leukocyte antigens (HLA), mediate both an immunotherapeutic effect and the risk of damage to healthy tissues ('graft-versus-host disease'). The adoption of evidencebased strategies for donor selection has been crucial for the continuous improvement of survival rates after allogeneic HCT, with over 50
KW  - Humans
KW  - Donor Selection
KW  - Hematopoietic Stem Cell Transplantation
KW  - Graft vs Host Disease: prevention & control
KW  - Unrelated Donors
KW  - Leukemia, Myeloid, Acute
KW  - HLA Antigens
KW  - Retrospective Studies
KW  - HLA Antigens (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:36949660
C2  - pmc:PMC10366961
DO  - DOI:10.3238/arztebl.m2023.0031
UR  - https://inrepo02.dkfz.de/record/277884
ER  -