%0 Journal Article
%A Karimian-Jazi, Kianush
%A Vollherbst, Dominik F
%A Schwarz, Daniel
%A Fischer, Manuel
%A Schregel, Katharina
%A Bauer, Gregor
%A Kocharyan, Anna
%A Sturm, Volker
%A Neuberger, Ulf
%A Jesser, Jessica
%A Herweh, Christian
%A Ulfert, Christian
%A Hilgenfeld, Tim
%A Seker, Fatih
%A Preisner, Fabian
%A Schmitt, Niclas
%A Charlet, Tobias
%A Hamelmann, Stefan
%A Sahm, Felix
%A Heiland, Sabine
%A Wick, Wolfgang
%A Ringleb, Peter A
%A Schirmer, Lucas
%A Bendszus, Martin
%A Möhlenbruch, Markus A
%A Breckwoldt, Michael O
%T MR microscopy to assess clot composition following mechanical thrombectomy predicts recanalization and clinical outcome.
%J Journal of neuroInterventional surgery
%V 16
%N 8
%@ 1759-8478
%C London
%I BMJ Journals
%M DKFZ-2023-01563
%P 830-837
%D 2024
%Z 2024 Jul 16;16(8):830-837
%X Mechanical thrombectomy (MT) is the standard of care for patients with a stroke and large vessel occlusion. Clot composition is not routinely assessed in clinical practice as no specific diagnostic value is attributed to it, and MT is performed in a standardized 'non-personalized' approach. Whether different clot compositions are associated with intrinsic likelihoods of recanalization success or treatment outcome is unknown.We performed a prospective, non-randomized, single-center study and analyzed the clot composition in 60 consecutive patients with ischemic stroke undergoing MT. Clots were assessed by ex vivo multiparametric MRI at 9.4 T (MR microscopy), cone beam CT, and histopathology. Clot imaging was correlated with preinterventional CT and clinical data.MR microscopy showed red blood cell (RBC)-rich (21.7
%K Stroke (Other)
%K Thrombectomy (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37527928
%R 10.1136/jnis-2023-020594
%U https://inrepo02.dkfz.de/record/277903