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@ARTICLE{Onyedibe:278340,
author = {M. C. C. Onyedibe$^*$ and P. Blickle$^*$ and M. Schmidt$^*$
and K. Steindorf$^*$},
title = {{P}osttraumatic growth and health-related quality of life
in cancer survivors: {D}oes fatigue moderate the link?},
journal = {Stress and health},
volume = {40},
number = {2},
issn = {1532-3005},
address = {Chichester [u.a.]},
publisher = {Wiley},
reportid = {DKFZ-2023-01597},
pages = {e3299},
year = {2024},
note = {#EA:C110#LA:C110# / 2024 Apr;40(2):e3299},
abstract = {Interest in post-traumatic growth (PTG) as a predictor of
health-related quality of life (HRQoL) is currently gaining
attention. However, current evidence is still inconclusive
on the nature of this relationship. The first objective of
this study was to investigate the relationship between PTG
and global HRQoL among cancer survivors. We further
investigated the moderating role of fatigue in the
association between PTG and global HRQoL. In the FiX study
(Fatigue in Germany - Examination of prevalence, severity,
and state of screening and treatment) cancer-related fatigue
(EORTC QLQ-FA12), PTG inventory and global HRQoL (EORTC
QLQ-C30) were assessed four years after cancer diagnosis in
1316 cancer-free survivors (mean age = 67.28, SD = 11.05,
$51.4\%$ female). Multiple linear regression analysis and
moderation analysis were performed. The results showed that
PTG had a convex quadratic relationship with global HRQoL (p
< 0.001). Contrary to our hypothesis, fatigue did not
moderate the relationship between PTG (linear and quadratic
terms) and global HRQoL, neither when considering the
overall PTG score nor for any PTG subdimension. In
conclusion, PTG has a convex quadratic relationship with
long-term global HRQoL that was not modified by persisting
fatigue. Future statistical models investigating PTG and
global HRQoL should take this non-linear relationship into
account. Aiming to increase PTG might contribute to, but is
likely not sufficient for high levels of global HRQoL in
cancer survivors in the long run.},
keywords = {cancer survivors (Other) / fatigue (Other) / post-traumatic
growth (Other) / psycho-oncology (Other) / quality of life
(Other) / survivorship (Other)},
cin = {C110},
ddc = {610},
cid = {I:(DE-He78)C110-20160331},
pnm = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
pid = {G:(DE-HGF)POF4-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:37547957},
doi = {10.1002/smi.3299},
url = {https://inrepo02.dkfz.de/record/278340},
}