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000278407 0247_ $$2ISSN$$a1361-6560
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000278407 1001_ $$0P:(DE-He78)8b9e41d8fdbc77efc053f339f24458f2$$aMarot, Mathieu$$b0$$eFirst author$$udkfz
000278407 245__ $$aMonte Carlo simulation for proton dosimetry in magnetic fields: Fano test and magnetic field correction factors kBfor Farmer-type ionization chambers.
000278407 260__ $$aBristol$$bIOP Publ.$$c2023
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000278407 500__ $$a#EA:E040#LA:E040# / Phys. Med. Biol. 68 (2023) 175037
000278407 520__ $$aIn this contribution we present a special Fano test for charged particles in presence of magnetic fields in the MC code TOPAS, as well as the determination of magnetic field correction factors kBfor Farmer-type ionization chambers using proton beams.&#xD;&#xD;Approach: Customized C++ extensions for TOPAS were implemented to model the special Fano tests in presence of magnetic fields for electrons and protons. The Geant4-specific transport parameters,DRoverRandfinalRange, were investigated to optimize passing rate and computation time. The kBwas determined for the Farmer-type PTW 30013 ionization chamber, and 5 custom built ionization chambers with same geometry but varying inner radius, testing magnetic flux density ranging from 0 to 1.0 T and two proton beam energies of 157.43 and 221.05 MeV.&#xD;&#xD;Main results: Using the investigated parameters, TOPAS passed the Fano test within 0.39±0.15% and 0.82±0.42%, respectively for electrons and protons. The chamber response (kBMQ) gives a maximum at different magnetic flux densities depending of the chamber size, 1.0043 at 1.0 T for the smallest chamber and 1.0051 at 0.2 T for the largest chamber. The local dose difference cBremained ≤ 0.1% for both tested energies. The magnetic field correction factor kB, for the chamber PTW 30013, varied from 0.9946 to 1.0036 for both tested energy.&#xD;&#xD;Significance: The developed extension for the special Fano test in TOPAS MC code with the adjusted transport parameters, can accurately transport electron and proton particles in magnetic field. This makes TOPAS a valuable tool for the determination of kB. The ionization chambers we tested showed that kBremains small (<0.7%). To the best of our knowledge, this is the first calculations of kBfor proton beams. This work represents a significant step forward in the development of MRgPT and protocols for proton dosimetry in presence of magnetic field.&#xD.
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000278407 650_7 $$2Other$$aMR-guided proton therapy
000278407 650_7 $$2Other$$aTOPAS
000278407 650_7 $$2Other$$adosimetry
000278407 650_7 $$2Other$$amagnetic field
000278407 650_7 $$2Other$$amagnetic field correction factor
000278407 7001_ $$0P:(DE-He78)ceed8085bb2faf0ec822fe89e8a085d3$$aJäger, Fabian$$b1$$udkfz
000278407 7001_ $$0P:(DE-He78)bf44d68f90110cc79436dbb10f477518$$aGreilich, Klaus-Steffen$$b2
000278407 7001_ $$0P:(DE-He78)b43076fb0a30230e4323887c0c980046$$aKarger, Christian P$$b3$$udkfz
000278407 7001_ $$00000-0002-6056-9747$$aJaekel, Oliver$$b4
000278407 7001_ $$0P:(DE-He78)914adea2baeb4f2c6a29637da6500048$$aBurigo, Lucas Norberto$$b5$$eLast author$$udkfz
000278407 773__ $$0PERI:(DE-600)1473501-5$$a10.1088/1361-6560/acefa1$$p175037$$tPhysics in medicine and biology$$v68$$x0031-9155$$y2023
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