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024 7 _ |a 10.1088/1361-6560/acefa1
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037 _ _ |a DKFZ-2023-01641
041 _ _ |a English
082 _ _ |a 530
100 1 _ |a Marot, Mathieu
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245 _ _ |a Monte Carlo simulation for proton dosimetry in magnetic fields: Fano test and magnetic field correction factors kBfor Farmer-type ionization chambers.
260 _ _ |a Bristol
|c 2023
|b IOP Publ.
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500 _ _ |a #EA:E040#LA:E040# / Phys. Med. Biol. 68 (2023) 175037
520 _ _ |a In this contribution we present a special Fano test for charged particles in presence of magnetic fields in the MC code TOPAS, as well as the determination of magnetic field correction factors kBfor Farmer-type ionization chambers using proton beams. Approach: Customized C++ extensions for TOPAS were implemented to model the special Fano tests in presence of magnetic fields for electrons and protons. The Geant4-specific transport parameters,DRoverRandfinalRange, were investigated to optimize passing rate and computation time. The kBwas determined for the Farmer-type PTW 30013 ionization chamber, and 5 custom built ionization chambers with same geometry but varying inner radius, testing magnetic flux density ranging from 0 to 1.0 T and two proton beam energies of 157.43 and 221.05 MeV. Main results: Using the investigated parameters, TOPAS passed the Fano test within 0.39±0.15% and 0.82±0.42%, respectively for electrons and protons. The chamber response (kBMQ) gives a maximum at different magnetic flux densities depending of the chamber size, 1.0043 at 1.0 T for the smallest chamber and 1.0051 at 0.2 T for the largest chamber. The local dose difference cBremained ≤ 0.1% for both tested energies. The magnetic field correction factor kB, for the chamber PTW 30013, varied from 0.9946 to 1.0036 for both tested energy. Significance: The developed extension for the special Fano test in TOPAS MC code with the adjusted transport parameters, can accurately transport electron and proton particles in magnetic field. This makes TOPAS a valuable tool for the determination of kB. The ionization chambers we tested showed that kBremains small (<0.7%). To the best of our knowledge, this is the first calculations of kBfor proton beams. This work represents a significant step forward in the development of MRgPT and protocols for proton dosimetry in presence of magnetic field. .
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650 _ 7 |a MR-guided proton therapy
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650 _ 7 |a TOPAS
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650 _ 7 |a dosimetry
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650 _ 7 |a magnetic field
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650 _ 7 |a magnetic field correction factor
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700 1 _ |a Jäger, Fabian
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700 1 _ |a Greilich, Klaus-Steffen
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700 1 _ |a Karger, Christian P
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700 1 _ |a Jaekel, Oliver
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700 1 _ |a Burigo, Lucas Norberto
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773 _ _ |a 10.1088/1361-6560/acefa1
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