Home > Publications database > Monte Carlo simulation for proton dosimetry in magnetic fields: Fano test and magnetic field correction factors kBfor Farmer-type ionization chambers. > print |
001 | 278407 | ||
005 | 20240229155034.0 | ||
024 | 7 | _ | |a 10.1088/1361-6560/acefa1 |2 doi |
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024 | 7 | _ | |a 0031-9155 |2 ISSN |
024 | 7 | _ | |a 1361-6560 |2 ISSN |
037 | _ | _ | |a DKFZ-2023-01641 |
041 | _ | _ | |a English |
082 | _ | _ | |a 530 |
100 | 1 | _ | |a Marot, Mathieu |0 P:(DE-He78)8b9e41d8fdbc77efc053f339f24458f2 |b 0 |e First author |u dkfz |
245 | _ | _ | |a Monte Carlo simulation for proton dosimetry in magnetic fields: Fano test and magnetic field correction factors kBfor Farmer-type ionization chambers. |
260 | _ | _ | |a Bristol |c 2023 |b IOP Publ. |
336 | 7 | _ | |a article |2 DRIVER |
336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1693574303_4717 |2 PUB:(DE-HGF) |
336 | 7 | _ | |a ARTICLE |2 BibTeX |
336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
500 | _ | _ | |a #EA:E040#LA:E040# / Phys. Med. Biol. 68 (2023) 175037 |
520 | _ | _ | |a In this contribution we present a special Fano test for charged particles in presence of magnetic fields in the MC code TOPAS, as well as the determination of magnetic field correction factors kBfor Farmer-type ionization chambers using proton beams.
Approach: Customized C++ extensions for TOPAS were implemented to model the special Fano tests in presence of magnetic fields for electrons and protons. The Geant4-specific transport parameters,DRoverRandfinalRange, were investigated to optimize passing rate and computation time. The kBwas determined for the Farmer-type PTW 30013 ionization chamber, and 5 custom built ionization chambers with same geometry but varying inner radius, testing magnetic flux density ranging from 0 to 1.0 T and two proton beam energies of 157.43 and 221.05 MeV.
Main results: Using the investigated parameters, TOPAS passed the Fano test within 0.39±0.15% and 0.82±0.42%, respectively for electrons and protons. The chamber response (kBMQ) gives a maximum at different magnetic flux densities depending of the chamber size, 1.0043 at 1.0 T for the smallest chamber and 1.0051 at 0.2 T for the largest chamber. The local dose difference cBremained ≤ 0.1% for both tested energies. The magnetic field correction factor kB, for the chamber PTW 30013, varied from 0.9946 to 1.0036 for both tested energy.
Significance: The developed extension for the special Fano test in TOPAS MC code with the adjusted transport parameters, can accurately transport electron and proton particles in magnetic field. This makes TOPAS a valuable tool for the determination of kB. The ionization chambers we tested showed that kBremains small (<0.7%). To the best of our knowledge, this is the first calculations of kBfor proton beams. This work represents a significant step forward in the development of MRgPT and protocols for proton dosimetry in presence of magnetic field.
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536 | _ | _ | |a 315 - Bildgebung und Radioonkologie (POF4-315) |0 G:(DE-HGF)POF4-315 |c POF4-315 |f POF IV |x 0 |
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650 | _ | 7 | |a MR-guided proton therapy |2 Other |
650 | _ | 7 | |a TOPAS |2 Other |
650 | _ | 7 | |a dosimetry |2 Other |
650 | _ | 7 | |a magnetic field |2 Other |
650 | _ | 7 | |a magnetic field correction factor |2 Other |
700 | 1 | _ | |a Jäger, Fabian |0 P:(DE-He78)ceed8085bb2faf0ec822fe89e8a085d3 |b 1 |u dkfz |
700 | 1 | _ | |a Greilich, Klaus-Steffen |0 P:(DE-He78)bf44d68f90110cc79436dbb10f477518 |b 2 |
700 | 1 | _ | |a Karger, Christian P |0 P:(DE-He78)b43076fb0a30230e4323887c0c980046 |b 3 |u dkfz |
700 | 1 | _ | |a Jaekel, Oliver |0 0000-0002-6056-9747 |b 4 |
700 | 1 | _ | |a Burigo, Lucas Norberto |0 P:(DE-He78)914adea2baeb4f2c6a29637da6500048 |b 5 |e Last author |u dkfz |
773 | _ | _ | |a 10.1088/1361-6560/acefa1 |0 PERI:(DE-600)1473501-5 |p 175037 |t Physics in medicine and biology |v 68 |y 2023 |x 0031-9155 |
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